Diego de la Muerte/El Muerto

Wilmer Valderrama

Maria

Angie Cepeda

Zak

Joel David Moore

Sheriff Ezra Stone

Michael Parks

Aparicio

Tony Plana

The Monsignor

E.J. Callahan

Padre Somera

Tony Amendola

Sister Rosa

Maria Conchita Alonso

The Old Indian

Billy Drago

Tezcatlipoca (voice)

Alfonso Arau

Young Diego

Darien Dikeos

Celia

D. Taylor Loeb

The Nun

María Conchita Alonso

Coyote

Vince Lozano

Co-Worker

Michele Marsh

Cameo

Aldo Gonzalez

State Trooper

Brandon Molale

Mictlantecuhtli

Nathan Mussell

Latina

Araceli Najar

Remy

Michael Macoul

Coyote

Emilio Rivera

Deputy

Steve Wilcox

2nd Deputy

Saro Solis