When East Village theater Renaissance man Charles Busch's sexually salacious +Vampire Lesbians of Sodom first premiered on the New York stage in 1984, few would have suspected that the cross-dressing slice of kitsch theater would eventually be honored as one of the longest-running shows in off-Broadway history. A runaway hit with the underground art community that quickly found its way to the mainstream, +Vampire Lesbians of Sodom defied convention to become one of the hottest tickets in town, and eventually served to launch the career of a man known best for being a woman. Devastated by the death of his mother at a young age, Charles Busch escaped into the world of classic film before being spirited away from the suburbs by his caring aunt and encouraged to explore his creativity in Manhattan. Though originally rejected by a variety of directors who dismissed him as either "too odd," or "too gay," Busch eventually decided to take control of his destiny by writing his own plays and became one of the most celebrated figures in New York theater. From Busch's early success with the Theater-in-Limbo to his later success in film with Psycho Beach Party and Die Mommie Die, the remarkable story of the self-made theater phenomenon is explored in this documentary from filmmakers John Catania and Charles D. Ignacio.