Blade

Wesley Snipes

Whistler

Kris Kristofferson

Reinhardt

Ron Perlman

Nyssa

Leonor Varela

Scud

Norman Reedus

Damaskinos

Thomas Kretschmann

Nomak

Luke Goss

Chupa

Matt Schulze

Asad

Danny John-Jules

Snowman

Donnie Yen

Carter Kounen

Karel Roden

Verlaine

Marit Velle Kile

Priest

Tony Curran

Lighthammer

Daz Crawford

Rush

Santiago Segura

Golem

Marek Vasut

Blood Bank Doctor

Pete Lee-Wilson

Jigsaw

Samuel Le

Blood Bank Guard

Paul Kasey

Blood Bank Nurse

Andrea Miltner

Drug Dealer

Ladislav Beran

Blood Bank Guard

Jiri Sieber

Vampire with Exposed Spine

Bridge Markland

Blood Bank Guard

Jiří Maria Sieber

Reaper

Stuart Luis

Reaper

Ladislav Mohyla

Reaper

Jamie Wilson

Reaper

Jan Malik

Reaper

Jan Révai

Reaper

Mario Wild

Reaper

Tomáš Böhm

Reaper

Zdenek Bubák

Reaper

Jan Loukota

Reaper

Jan Bursa

Reaper

Petr Krusalnicky

Reaper

Jaroslav Misek

St. Cloud

Karel Vavrovec

Choad

Jaroslav Peterka

Little G

Milos Kulhavy

Tea Bag

Ivan Mares

Man in London Porno Shop

Lennox Brown

Young Blade

Andre Hyde-Braithwaite

Moscow Vampire

Pavel Cajzl

Prostitute

Olga Lounová

Reapers (voice)

Scott Martin Gershin

Paramedic

Stephen R. Peluso

Moscow Vampire Attacking Blade

John Salvitti

Moscow Vampire Attacking Blade

Kenji Tanigaki

Vanessa Brooks (uncredited)

Sanaa Lathan

Director

Guillermo Del Toro