Hosted by Neil Patrick Harris, who played one of TV's most celebrated prodigies, this new game show teams up whiz kids from across the country to face off in extraordinary challenges of the brain. Through a series of escalating rounds involving math, memory, logic, spelling and more, the kids are tested in different brain-teasing disciplines. In the final round, the top teams take part in The Cortex, the ultimate test of genius. The winning team takes home a prize that will help set the stage for their bright futures.