Clark Kent/Superman

Brandon Routh

Don Ricardo

Fred Coby

Lois Lane

Kate Bosworth

Dorothea

Isabelita

Miguel Porcarreno

Martin Garralaga

Lex Luthor

Kevin Spacey

Richard White

James Marsden

Don Jose Luerra

Anthony Warde

Perry White

Frank Langella

Lugo the Huge

Paul Newlan

Martha Kent

Eva Marie Saint

Kitty Kowalski

Parker Posey

Padre Carlos

David Leonard

Stanford

Kal Penn

Jimmy Olsen

Sam Huntington

Jor-El

Marlon Brando

Brutus

David Fabrizio

Jason White

Tristan Lake Leabu

Ben Hubbard

James Karen

Riley

Ian Roberts

Gertrude Vanderworth

Noel Neill

Grant

Vincent Stone

Bobbie-Faye

Peta Wilson

Bo the Bartender

Jack Larson

Young Clark Kent

Stephan Bender

Boy with Camera

Keegan Joyce

Gil

Jeff Truman

Little Girl

Jordana Beatty

Polly

Barbara Angell

Bank Gunner

Rob Flanagan

Shuttle Commander

Ian Bliss

Shuttle Pilot

Ansuya Nathan

777 Co-Pilot

Warwick Young

Shuttle Engineer

Richard Branson

777 Navigator

Bradd Buckley

Mission Control Flight Director

Bill Young

Mission Control Officer

David Webb

Museum Guard

Patricia Howson

Mission Control Navigator

Thomas Stewart

777 Navigator

Brad Buckley

Vanderworth Relative No. 1

Mirren Lee

Hospital Ward Nurse

Karina Bracken

Vanderworth Relative No. 2

Steve Ostrow

Vanderworth Relative No. 3

Hank Roberts

Hospital Nurse

Raelee Hill

French News Anchor (as Frederique Fouché)

Frederique Fouche

German Reporter

Rebecca Barratt

Doctor No. 1

Lee James

Doctor No. 2

Michael Duggan

Hospital Reporter #8

Karen Pang

EMT (uncredited)

Jennifer Sciole

British Scientist

Donald MacDonald

German News Anchor

Julian Pulvermacher

Cape Canaveral Reporter

Robert Meyer Burnett

News Anchor No. 1

Ted Maynard

News Anchor No. 2

Ed Wightman

News Anchor No. 3

Prue Lewarne

News Anchor No. 4

Paul Shedlowich

News Anchor No. 5

Barry Quin

News Anchor No. 6

Francine Bell

Sydney Reporter

Penelope Heath

Reporter at Deli

Genevieve Davis

Hospital Policeman

Terrell Dixon

Security Guard No. 1

Kevin Fisher

Security Guard No. 2

John Lucantonio

Home Plate Umpire

Darin Rossi

Police Sharp Shooter

Phillip Henry

Taxi Driver

Henry Browne

Shuttle Specialist

Sam Branson