Luke Cage

Mike Colter

Mariah Dillard

Alfre Woodard

Misty Knight

Simone Missick

Claire Temple

Rosario Dawson

Cornell "Cottonmouth" Stokes

Mahershala Ali

Shades

Theo Rossi

Rafael Scarfe

Frank Whaley

John McIver/Bushmaster

Mustafa Shakir

Detective Mark Bailey

Justin Swain

Tilda Johnson

Gabrielle Dennis

Rosalie Carbone

Annabella Sciorra

Sugar

Sean Ringgold

Soledad Temple

Sonia Braga

Willis 'Diamondback' Stryker

Erik LaRay Harvey

Bobby Fish

Ron Cephas Jones

Alex Wesley

John Clarence Stewart

Inspector Priscilla Ridley / Deputy Chief Priscilla Ridley

Karen Pittman

D.W. Griffith

Jeremiah Craft

Zip

Jaiden Kaine

Sheldon Shaw

Kevin Mambo

Anansi

Sahr Ngaujah

Detective Nandi Tyler

Antonique Smith

Comanche

Thomas Q. Jones

James Lucas / James Lucas (voice)

Reg E. Cathey

Captain Tom Ridenhour

Peter J. Fernandez

Auntie Ingrid

Heather Simms

Ben Donovan

Danny Johnson

Thembi Wallace

Tijuana Ricks

Raymond 'Piranha' Jones

Chaz Lamar Shepherd

Domingo Colon

Jacob Vargas

Candace

Deborah Ayorinde

Connie Lin

Jade Wu

Lonnie Wilson

Darius Kaleb

Stephanie aka Billie

Tarah Rodgers

Captain Betty Audrey

Sonja Sohn

Dr. Noah Burstein

Michael Kostroff

Megan McClaren / Megan McLaren

Dawn-Lyen Gardner

Dontrell 'Cockroach' Hamilton

Dorian Missick

Reva Connors

Parisa Fitz-Henley

Goon One / Goon

Jamar Greene

Patricia Wilson

Cassandra Freeman

Turk Barrett

Rob Morgan

Wilfredo 'Chico' Diaz

Brian Marc

Lieutenant Perez

Manny Pérez

Amos

R. Marcos Taylor

Teenage Carl Lucas / Teenage Carl

Clifton Cutrary

Damon Boone

Clark Jackson

Teenage Willis Stryker

Jared Kemp

Sergeant Jacob 'Jake' Smith

Lee R. Sellars

ESU Lieutenant Mario Green

P.J. Marshall

Jin Lin

Clem Cheung

Drea Powell

Michelle Beck

Detective Donnie Chang / Detective Chang

Andrew Pang

D-Nice

D‐Nice

Reporter 1 / Male Reporter / Reporter #1

Tristan Laurence Perez

Aisha Axton

Ninja N. Devoe

Goon Three

Truck Hudson

Director

Lucy Liu