Dr. Mark Greene

Anthony Edwards

Kerry Weaver

Laura Innes

Dr. Peter Benton

Eriq La Salle

Dr. Doug Ross

George Clooney

Dr. John Carter

Noah Wyle

Dr. Susan Lewis

Sherry Stringfield

Abby Lockhart

Maura Tierney

Head Nurse Carol Hathaway

Julianna Margulies

Dr. Elizabeth Corday

Alex Kingston

Nurse Haleh Adams

Yvette Freeman

Dr. Luka Kovac

Goran Visnjic

Ozzie Sheff

Andrew Ferchland

Jennifer Greene / Jennifer Simon

Christine Harnos

Jason Warren

Charley Lang

Samuel Gasner

Alan Rosenberg

Mr. Franks

John Randolph

Dr. Janet Coburn

Amy Aquino

Dr. Arndt

Douglas Rowe

Chuny Marquez

Laura Cerón

Andy Bohlmeyer

Jared Rushton

Mr. Layton

Byron Stewart

Nurse Lily Jarvik

Lily Mariye

Robert Romano

Paul McCrane

Mr. Conally

Bobcat Goldthwait

David Morgenstern

William H. Macy

Jimmy Falco

Matt Borlenghi

Janette Ryan

Ashley Malinger

Dr. Jack Kayson

Sam Anderson

Mrs. Lafferty

Julie Carmen

Mrs. Sheff

Annabella Price

Tracy Young

Holly Gagnier

Jake Leeds

Zachary Browne

Mrs. Dibble

Debra Jo Rupp

Mr. Cheung

Ping Wu

Ryan

Kathleen Dennehy

Ms. Brown

Lili Flanders

Sandy's Mother

Kimberly Scott

Arlena

Kimmy Robertson

Linda Farrell

Andrea Parker

Priscilla

Patricia Healy

Dr. Sarah Langworthy

Tyra Ferrell

Cleo Finch

Michael Michele

Howard Davis

Carmen Argenziano

Dr. Wilson

Dennis Lipscomb

Mr. Gaither

John Marshall Jones

Nurse Malik McGrath

Deezer D

Liz

Liz Vassey

Amy

Catherine Lloyd Burns

Thornberg's Friend

Karmin Murcelo

Jamie Hendricks

Brigid Walsh

Mrs. Gainsley

Peggy Pope

Victor

Ed Cambridge

Alan

Neil Giuntoli

Frank Cheung

Joseph Ung

Jing-Mei Chen

Ming-Na Wen

Henry Colton/Rena

Vondie Curtis-Hall

Dave Malucci

Erik Palladino

Al Boulet

Wolfgang Bodison

Timmy Rawlins

Glenn Plummer

Boy's Father

Michael Bowen

Mr. Desmond

John Doolittle

Mrs. Powell

Cynthia Ettinger

Blum

Susan Merson

Nurse Wendy Goldman

Vanessa Marquez

Mae Benton

Beah Richards

Sister

Amy Ryan

Mrs. Abernathy

Priscilla Pointer

Mr. Freeman

Richard Brooks

Jeanie Boulet

Gloria Reuben

Doris Pickman / Pickman

Emily Wagner

Jackie Robbins

Khandi Alexander

Patrick

Kevin Michael Richardson

Mrs. Rose

Meg Foster

Francis

Graham Jarvis

Munch

Bruce Gray

Dr. Angela Hicks

CCH Pounder

Mrs. Heizer

Eda Reiss Merin

Kallis

David Purdham

Dr. David 'Div' Cvetic

John Terry

Mookie 'Slice' James

Christian Coleman

Diane Leeds

Linda Kelsey

Mary Cavanaugh/'Madame X'

Rosemary Clooney

Jodi O'Brien

Colleen Flynn

Jerry Markovic

Abraham Benrubi

Smiley

Gregory Millar

Guest Star

Steve Eastin

Harry Stopak

Ken Lerner

Elaine Gasner

Cathy Lind Hayes

Roxanne

Alix Elias

Chloe Lewis

Kathleen Wilhoite

Diane Leeds

Lisa Zane

Mrs. Packer

Anne Haney

Dr. John 'Tag' Taglieri

Rick Rossovich

Hospital Administrator

Tobin Bell

Walter Robbins

Ving Rhames

Gilbert McCabe

Keene Curtis

Cookie Lewis

Valerie Perrine

Monty

Paul Perri

Ronnie - Chloe's Boyfriend

Courtney Gains

Sean O'Brien

Brad Whitford