Voice

Konstantinos Markoulakis

Mrs. Little

Geena Davis

Stuart Little

Kasper van Kooten

Stuart Little (voice)

Michael J. Fox

Eleanor Little

Frédérique Huydts

Voice

George Mataragas

Mr. Little

Hugh Laurie

Voice

George Petrochilos

Fredrick Little

Peter Blok

George Little

Jonathan Lipnicki

Voice

Pavlos Kontogiannidis

George Little

Quinten Schram

Cousin Edgar

Brian Doyle-Murray

Voice

Dino Soutis

Snowbell

Carol van Herwijnen

Snowbell (voice)

Nathan Lane

Grandma Estelle

Estelle Getty

Voice

Spyros Bibilas

Smokey

Frits Lambrechts

Mrs. Keeper

Julia Sweeney

Smokey (voice)

Chazz Palminteri

Monty the Mouth

Johnny Kraaijkamp Jr.

Dr. Beechwood

Dabney Coleman

Monty (voice)

Steve Zahn

Lucky

Frans van Deursen

Lucky (voice) / Officer Allen

Jim Doughan

Camille Stout

Wanda Joosten

Red (voice)

David Alan Grier

Mr. Stout (voice)

Bruno Kirby

Mrs. Stout (voice)

Jennifer Tilly

Race Announcer (voice)

Stan Freberg

Uncle Crenshaw

Jeffrey Jones

Aunt Tina

Connie Ray

Aunt Beatrice

Allyce Beasley

Grandpa Spencer

Harold Gould

Uncle Stretch

Patrick Thomas O'Brien

Westleigh Michael Styer

Boat Registrar

Larry Goodhue

Anton

Miles Marsico

Crowd Person

Richard Alan Hicks

Officer Sherman

Jon Polito

Race Starter

Joe Bays

Salesman

Taylor Negron

Race Spectator

Kimmy Robertson

Hot Dog Vendor

Tannis Benedict

Skipper

Chuck Blechen

Skipper

Westleigh M. Styer

New Yorker (uncredited)

Joshua Paule

Marietta Meade

Walter von Hauff

Raban Bieling

Fred Klaus

Anita Höfer

Götz Otto

Margit Weinert

Tonio von der Meden

Bastian Pastewka

Inez Günther

Pierre Peters-Arnolds

Michael Rüth

Tobias Lelle

Cynthia Songe