Billy Butcher

Karl Urban

Hugh 'Hughie' Campbell

Jack Quaid

Madelyn Stillwell

Elisabeth Shue

Homelander

Anthony Starr

Reggie Franklin / A-Train

Jessie T. Usher

Annie January / Starlight

Erin Moriarty

Maggie Shaw / Queen Maeve

Dominique McElligott

Kevin Moskowitz / The Deep

Chace Crawford

Marvin T. 'Mother's Milk' Milk / M.M.

Laz Alonso

Earving / Black Noir / Black Noir II

Nathan Mitchell

Frenchie

Tomer Capon

Kimiko Miyashiro

Karen Fukuhara

Ashley Barrett

Colby Minifie

Stormfront

Aya Cash

Ryan

Cameron Crovetti

Stan Edgar / Meerkat Stan Edgar (voice)

Giancarlo Esposito

Patton Oswalt

Victoria 'Vic' Neuman

Claudia Doumit

Jessica Bradley / Sister Sage

Susan Heyward

Goran Visnijc

Misty Tucker Gray / Firecracker

Valorie Curry

Seth Reed

Malcolm Barrett

NNC News Anchor / Female News Anchor / Nneka Elliott

Nneka Elliott

Ben / Soldier Boy

Jensen Ackles

Grace Mallory

Laila Robins

Becca Butcher

Shantel VanSanten

PJ Byrne

Cherie

Jordana Lajoie

Cassandra

Katy Breier

Cameron Coleman

Matthew Edison

Secretary of Defense Robert A. Singer

Jim Beaver

Hugh Campbell

Simon Pegg

Nathan

Christian Keyes

Joe Kessler

Jeffrey Dean Morgan

Oh Father

Daveed Diggs

Donna January

Ann Cusack

Elena

Nicola Correia Damude

Also Ashley

Sabrina Saudin

Janine

Liyou Abere

Susan Rayner

Jennifer Esposito

Evan Lambert

David Reale

Zoe Neuman

Olivia Morandin

Monique

Frances Turner

Todd

Matthew Gorman

Daphne Campbell

Rosemarie DeWitt

Crimson Countess / Fox Crimson Countess (voice)

Laurie Holden

Senator Calhoun

David Andrews

Ezekiel

Shaun Benson

Carol

Jessica Hecht

Shockwave

Mishka Thébaud

Adam Bourke

P. J. Byrne

Little Nina

Katia Winter

Anika

Ana Sani

Sameer Shah

Omid Abtahi