Earl Sinclair (voice)

Stuart Pankin

Fran Sinclair

Jessica Walter

B.P. Richfield (voice)

Sherman Hemsley

Roy Hess (voice) / John (voice) / Absolute Proof Laboratories Scientist (voice)

Sam McMurray

Robbie Sinclair

Jason Willinger

Charlene Sinclair

Sally Struthers

Baby Sinclair

Kevin Clash

Grandma Ethyl

Florence Stanley

Gary

Steve Landesberg

Mel Luster

Richard Portnow

Arthur Rizzic

Brian Henson

Dinosaur Chief

Harold Gould

Mr. Ugh

Michelan Sisti

Monica Devertebrae (voice) / Thighs of Thunder (voice) / Elder #3 (voice)

Suzie Plakson

Mr. Pulman (voice) / Monster (voice) / Dr. Elliot Piaget (voice)

Allan Trautman

Guy in the Lab Coat (voice) / Bryant (voice) / Police Chief Parish (voice)

Michael McKean

Spike (voice)

Christopher Meloni

Chef (voice) / Ed (voice) / Richard (voice)

Thom Sharp

Mindy (voice) / Sitcom Wife (voice) / Vendor (voice)

Jessica Lundy

Gus Molehill (voice) / Stu (voice) / The Job Wizard (voice)

Jason Alexander

Fox Jacket (voice) / Henri Poupon (voice) / Pterodactyl (voice)

Tim Curry

WeSaySoCorp Announcer (voice) / Television Announcer (voice) / Elder in Chief (voice)

Michael Dorn

Timmy (voice) / Wereman (voice)

Kirk R. Thatcher

Narrator (voice)

Gary Owens

News Bulletin Announcer (voice) / USO Stage Manager (voice) / TV Announcer (voice)

Chuck Varesko