James

John Travolta

Mollie

Kirstie Alley

Rosie

Olympia Dukakis

Stuart

Elias Koteas

głos Mikey

Bruce Willis

Julie

Roseanne Barr

Rona

Twink Caplan

Joey

Gilbert Gottfried

Eddie (voice)

Damon Wayans

Mikey

Lorne Sussman

Mr. Toilet Man (voice)

Mel Brooks

Julie, age 1

Megan Milner

Julie, age 4 months

Georgia Keithley

Eddie

Danny Pringle

Julie, as a Newborn

Nikki Graham

Dr. Fleischer

Don S. Davis

Lou

Louis Heckerling

Mr. Ross

Neal Israel

Burglar

Rick Avery

Debbie

Lesley Ewen

Woman Client

Noelle Parker

Man Client

Douglas Warhit

IRS Inspector

Terry David Mulligan

Taxi Businessman

Paul Shaffer

Arrogant Businessman

Morris Panych

Needle Doctor

Alex Bruhanski

Blonde

Dorothy Fehr

Hot Babe on Fire Escape

Heather Lea Gerdes

Cool Chick

Robin Trapp

Fire Chief

Stephen Dimopoulos

Punk Baby

Jimmy Galeota

Stuart Aikins

Candy Man

Frank Totino

Businessman's Babe

Ruby J. Munro

Cute Guy

Randy Aaron Fink

Mikey's Dream Friend

Mollie Heckerling

Cop (uncredited)

Denis Corbett

Shopper (uncredited)

Yolanda Corbett

Mikey's Dream Friend

Mollie Israel