Lou

Susan Sarandon

Narrator

Byron Cadwell

Marilyn

Bette Midler

Alice

Megan Mullally

Kitty

Sheryl Lee Ralph

Captain Ernie

Timothy V. Murphy

Amanda

Sophie von Haselberg

Ted

Bruce Greenwood

Dr. Rhonda Brown(as Déjà Dee)

Deja Dee

Nathan

Kadan Well Bennett

Michael Bolton

Michael Bolton

Shivani

Renika Williams

Leslie

Brandee Evans

Sheila

Abigail Dolan

Officiant

John Crosby

Bobby(as Kaden Joel Taylor)

Kaden Taylor

Aimee

Avangeline Friedlander

Brandon

David Goren

Young bridal assistant

Molly Hargrave

Joaquin

Nicholas Velez

Bartender

Micah Engle

Cute Guy

Lex Lauletta

Nurse(as Thao Lee)

Thao Le

Handsome Champagne Waiter (uncredited)

Zachary Vazquez

Airline Stewardess (uncredited)

Angela Lentz

Wedding Planner (uncredited)

Pamela Hardy

Wedding Caterer (uncredited)

Mitchell Patrick Greene

Airline Passenger (uncredited)

Mike Bevins

Soiree Attendee (uncredited)

Art Newkirk

Restaurant Patron (uncredited)

Joseph D. Webb