Michael Knight

David Hasselhoff

Devon Miles

Edward Mulhare

Bonnie Barstow

Patricia McPherson

Karen Forester

Janine Turner

Reginald Cornelius III

Peter Parros

K.I.T.T. (voice)

William Daniels

Jeff Cavanaugh

Robert F. Lyons

Marco Berio

Harvey Jason

April Curtis

Rebecca Holden

Guest Star

Jonathan Goldsmith

Donald Crane

Henry Gibson

Guest Star

Aharon Ipalé

Victor Gavin

Michael Callan

Simon Carascas

Walter Gotell

Julie Rogers

Julianne McNamara

Charles Zurich

Ron O'Neal

Bronwyn Appleby

Andrea Howard

Guest Star

Mark Venturini

Guest Star

Denise Galik

Amy Lowell

D.D. Howard

Guest Star

Lina Raymond

Scott Holliman

Mark Schneider

Samantha Dutton

Nancy Everhard

Royal Davis

Terry Kiser

Wayne Altfield

William Windom

Austin Templeton

Lance Burton

Phillip Nordstrom

John Considine

Julian Martin

Daniel Faraldo

Cyrus Oakes

Robert Pine

Guest Star

Ken Swofford

Tess Hubbard

Zohra Lampert

Guest Star

Reid Smith

Guest Star

Shelley Berman

Vince

Nicholas Pryor

Susan Christopher

Gina Gallego

Darryl

David Raynr

Guest Star

Miguel Fernandes

Calvin Holmes

Macon McCalman

Jennifer Knight

Mary Kate McGeehan

Mel Tobey

Antony Ponzini

Erik Whitby

J. Eddie Peck

Jean Tremont

Kat Sawyer-Young

Mac Thomas

John Crawford

Guest Star

Nick Angotti

Vascone

Kabir Bedi

Guest Star

Kathy Shower

Jason Nelson

Peter Brown

Guest Star

George Kee Cheung

Harana

Rosalind Cash

Ariel Marsden

Hurd Hatfield

Nicholas Arkett

Gary Hershberger

Guest Star

Ada Maris

Stephanie 'Stevie' Mason

Catherine Hickland

Guest Star

Paul Carafotes

Elena Thomas

Jourdan Fremin

Elizabeth Wesley

Christie Hauser

Guest Star

Kip Niven

Guest Star

Rummel Mor

Dr. Thorne

Ron Soble

Henry Quincy

Arthur Batanides

Steven

Dennis Pratt

Christine Brooks

Victoria Bass

Karen Bennett

Lenore Kasdorf

Nancy Marsden

Mary Beth Evans

Sandra Rusk

Nana Visitor

Jim Hower

Nicholas Worth

Ellen Whitby

P.J. Soles

Lupo

Pepe Serna

Snyder

Robert O'Reilly

Colton

Scott Valentine

Ruth Keeler

Tracy Reed

Crossing Guard

Anne Ramsey

Gaye Hollenbeck

Beth Miller

Chuck

Paul Brinegar

Claude Watkins

John Vernon

Guest Star

Eloy Casados

Guest Star

Sharon Acker

Steve Cochran

Grainger Hines

Guest Star

Henry Darrow

Dr. Quentin Tanner

George O. Petrie

Benson

John Snyder

Guest Star

Robert Feero

Gordon

Andy Epper

Guest Star

Bill Saito

Dr. Von Furst

Mary Woronov

Edward Kent

Robert Englund

Nick

Robbie Rist

Hitchhiker

Charles Fleischer

Wilson

Vernon Wells

Guest Star

William Jordan

Jonathan Dutton

M.C. Gainey

Guest Star

Stephen Meadows

Dr. Klaus Bergstrom / Kleist

Peter Mark Richman

Guest Star

Norman Burton

Guest Star

Michael Chong

Pete - Truck Driver / Federal Agent / Janetti

Bruce Neckels

Guest Star

Rosalind Ingledew

Liz Preston

Leann Hunley

Nicholas Farrell

Tony Epper

Guest Star

Tom Simcox