Secret Service Man #1 / Lieutenant (voice)

Rob Letterman

Susan Murphy / Ginormica (voice)

Reese Witherspoon

Commander / Advisor Smith (voice)

Bo Dietl

Dr. Cockroach Ph.D.

Hugh Laurie

B.O.B. (voice)

Seth Rogen

The Missing Link

Will Arnett

Gallaxhar (voice)

Rainn Wilson

General W.R. Monger

Kiefer Sutherland

Derek Dietl (voice)

Paul Rudd

Gallaxhar

Rainn Wilson

The President of the United States

Stephen Colbert

Wendy Murphy (voice)

Julie White

Carl Murphy (voice)

Jeffrey Tambor

Computer (voice)

Amy Poehler

News Reporter (voice)

Ed Helms

Katie (voice)

Renée Zellweger

Insectosaurus

Jimmy Kimmel

Private Bullhorn / Helicopter Pilot / Advisor Ortega (voice)

Sean Bishop

Bridesmaid Candy (voice)

Lisa Stewart

Louise Bourgoin

Stéphane Freiss

Wilson (voice)

Tom McGrath

Advisor Cole / Army Commander Jones (voice)

Chris Miller

Julien Doré

Advisor Wedgie (voice)

Mike Mitchell

Dorothée Pousséo

Gilbert Lévy

Technician Jerry (voice)

Kent Osborne

Nessym Guetat

Panicked Guest / Female Advisor #2 / Mrs. Ronson / Advisor O

Latifa Ouaou

Soldier #4 / Pilot / Soldier #3

Geoffrey Pomeroy

Soldier #1 / Advisor Jackson (voice)

David P. Smith

Advisor Hawk / Advisor Dither / Minister

Conrad Vernon

Stine Stengade

Diana Amft

Cuthbert (voice)

John Krasinski

Oliver Kalkofe

Technician Bee (voice)

Stephen Kearin

Erich Räuker

Ralph Moeller

Tobias Meister

Frank Schaff

Peter Flechtner

Sebastian Höffner

Monica Bielenstein

Rüdiger Evers

Ranja Bonalana

Vera Teltz

Olaf Reichmann

Werner Ziebig

Director

Peter Ramsey*

Director

Conrad Vernon

Director

Rob Letterman