Clark Griswold

Chevy Chase

Ellen Griswold

Beverly D'Angelo

Cousin Eddie Johnson

Randy Quaid

Nora Griswold

Diane Ladd

Audrey Griswold

Juliette Lewis

Clark Wilhelm Griswold, Sr.

John Randolph

Russell 'Rusty' Griswold

Johnny Galecki

Art Smith

E.G. Marshall

Frances Smith

Doris Roberts

Margo Chester

Julia Louis-Dreyfus

Aunt Bethany

Mae Questel

Aunt Bethany

Mae Questel

Uncle Lewis

William Hickey

Uncle Lewis

William Hickey

Cousin Catherine Johnson

Miriam Flynn

Mr. Frank Shirley

Brian Doyle Murray

Rocky

Cody Burger

Todd Chester

Nicholas Guest

Cousin Ruby Sue Johnson

Ellen Hamilton Latzen

Mary

Nicolette Scorsese

Bill

Sam McMurray

Billy Hopkins

Heidi Levitt

Delivery Boy

Keith MacKechnie

Helen Shirley

Natalija Nogulich

Bozo #1

Tony Epper

Bozo #2

Billy Hank Hooker

SWAT Officer

Alexander Folk

Cop

Jeremy Roberts

Bozo #2

Hank Hooker

Cop

Woody Weaver

Young Executive

Michael Kaufman

Parade Announcer (voice)

Doug Llewelyn

SWAT Team Sargeant

Frank Foti Jr.

Director

Jeremiah Chechik

Director

Jeremiah S. Chechik