El Mariachi

Antonio Banderas

CIA Agent Jeffrey Sands

Johnny Depp

Carolina

Salma Hayek

Belini

Cheech Marin

Billy Chambers

Mickey Rourke

CIA Agent Ajedrez

Eva Mendes

Armando Barillo

Willem Dafoe

Cucuy

Danny Trejo

Lorenzo

Enrique Iglesias

Fideo

Marco Leonardi

Jorge, Retired FBI Agent

Rubén Blades

Marquez

Gerardo Vigil

Romero

Troy Robinson

El Presidente

Pedro Armendáriz Jr.

Nicholas, Presidential Advisor

Julio Oscar Mechoso

Cab Driver

Tito Larriva

Dr. Guevera

Miguel Couturier

Chicle Boy

Tony Valdes

Alvaro

José Luis Avendaño

Omar(as Rodolfo d'Alejandre)

Rodolfo De Alexandre

Mariachi's Girl

Natalia Torres

Right Hand

Steven Constancio

Right Hand

Steve Constancio

Qui-Que

Ermahn Ospina

Pistolera

Luz María Rojas

Cook

Mario Simon

Blascoe

Bernard Hacker

Waitress

Cecilia Tijerina

Hospital Administrator

Carola Vázquez

Chief Federale

René Gatica

Bachelorette

Silvia Santoyo

Bull Fighter

Juan Pablo Llaguno

Teacher

Ignacio Torre

Manny

Rojo Grau

Taco

Jorge Becerril

Left Nut

Víctor Carpinteiro

Que Pasa

Dagoberto Gama

Bartender with Gun (uncredited)

Thomas Rosales Jr.

Soldier (uncredited)

Khristian Lupo