Dobie Gillis
Dwayne Hickman
Maynard G. Krebs
Bob Denver
Zelda Gilroy
Sheila James
Herbert T. Gillis
Frank Faylen
Mr. Leander Pomfritt
William Schallert
Winnie Gillis
Florida Friebus
Clarice Armitage/Mrs. Chatsworth Osborne Sr.
Doris Packer
Chatsworth Osborne Jr.
Steve Franken
Thalia Menninger
Tuesday Weld
Zelda Gilroy
Sheila James Kuehl
Milton Armitage
Warren Beatty
Riff Ryan
Tommy Farrell
Captain Lopez / Generalissimo Sebastien Romero / President Carlos Rubero
Alberto Morin
Melissa Frome
Yvonne Lime
Davey Gillis
Darryl Hickman
Officer Sam Parmalee / Committee President Hawley / Police Officer Bloodhound Mulcahey
Richard Reeves
Chrissie Tyler (as Mike Burns)
Michael Burns
Blossom Kenney
Marjorie Bennett
Mrs. Ruth Adams/Dr. Burkhart
Jean Byron
Max Perkins
Robert Paget
Guest Star
James Yagi
Guest Star
Diane Jergens
Fifi LaVerne / Molly O'Day
Carole Cook
Guest Star
Marjorie Bennett
Guest Star
Joel Crothers
Guest Star
Penny Parker
Guest Star
Jack Albertson
Guest Star
Willis Bouchey
Guest Star
Ron Howard
Guest Star
Alan Carney
Derek
David Frankham
Guest Star
Mel Blanc
Guest Star
Janice Carroll
Guest Star
Charles Watts
Guest Star
Milton Frome
Guest Star
Angelo De Meo
Guest Star
Bart Carlin
Mrs. Lapping
Verna Felton
Guest Star
Verna Felton
Guest Star
Ray Hemphill
Guest Star
Guy Lee
Guest Star
Sondra Rodgers
Guest Star
Michael J. Pollard
Guest Star
Colin Campbell
Hermione Krausmeyer
Gina Gillespie
Guest Star
Romney Tree
Guest Star
Douglas Odney
Guest Star
Barbara Riley
Telephone Operator (voice)
Bea Benaderet
Guest Star
Kay Stewart
Guest Star
Bill Tennant
Guest Star
Marlo Thomas
Guest Star
Stanley Adams
Guest Star
Herbert Anderson
Guest Star
Jim Johnson
Hazel Grimes
Yvonne Craig
Guest Star
Ryan O'Neal
Guest Star
Francis X. Bushman
Bobby Wilkins (as Donald Keeler)
Joey D. Vieira
Donna Whittaker
Ellen Burstyn