Pope Pius XIII/Lenny Belardo

Jude Law

Giovanni Paolo III / Sir John Brannox

John Malkovich

Monsignor Bernardo Alonso Gutierrez

Javier Cámara

Cardinal Angelo Voiello

Silvio Orlando

Ester Aubry

Ludivine Sagnier

Sofia Dubois

Cécile de France

Cardinal Mario Assente

Maurizio Lombardi

Cardinal Aguirre

Ramón García

Danny

Henry Goodman

Doctor Lindegard

Ulrich Thomsen

Bauer

Mark Ivanir

Stefano Accorsi

Cardinal Spalletta

Massimo Ghini

Ewa Nowak

Yuliya Snigir

Monsignor Luigi Cavallo

Antonio Petrocelli

Fabiano

Alessandro Riceci

Sharon Stone

Sharon Stone

Sister Lisette

Nora Waldstätten

Abbess of St. Therese

Kiruna Stamell

Donna Divisa Rossa

Kika Georgiou

Sister Caterina

Eco Andriolo Ranzi

Pius

Thomas Miggiano

Bauer's Girlfriend / Amber

Daria Baykalova

Faisal

Zaki Bibawi Ayyad

Don Mario

Massimo Cagnina

Sister Suree

Nadee Kammellaweera

Young John Brannox

Matthew Smallwood

Adam Brannox

Joshua Smallwood

—

Tony Allotta

Girolamo

Edoardo Bussi

Sister Ivanka

Agnieszka Jania

Sister Pamela

Jessica Piccolo Valerani

Thomas Altbruck

Tomas Arana

Don Mimmo

Marcello Marziali

Christian Erickson

—

Sergio Forconi

—

Guido Roncalli

—

Luciano Roffi

Emmanuel Dabone

—

Libero Sansavini

—

Osvaldo Alzari

—

Michael Fitzpatrick

—

Michelangelo Tarditti

Duillo Guicciardini

Claudio Bigagli

Attanasio

Enea Barozzi

Father Valente

Ignazio Oliva

Young Lady Brannox

Hella Stichlmair

Don Tommaso Viglietti

Marcello Romolo

Marilyn Manson

Marilyn Manson

Young Lord Brannox

Jonas Crodack

Franciscan

Giulio Della Monica

Franciscan

Nicolò Galasso

Priest

Giampaolo Nerini

Lady Brannox / —

Janet Henfrey

Nicolas Porcelli

Lord Brannox

Tim Barlow

John Brannox - 12

Calum Potts

Adam Brannox - 12

Charlie Potts

Reporter

Robert Brodie Booth

Vatican Photographer

Evandro Inetti

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Federica Corti

Attanasio's Mother

Lore Stefanek

Freddy Blakestone

Alex Esola

Marcella Sacco

Young Prostitute

Chiara Mocci

Domen

Daniel Vivian

Sky Journalist

Sinne Mutsaers

Fraticello

Gianluigi Calvani

—

Giorgio Braschi

—

Giorgio Isopi

—

Ian Sutton

—

John Henderson Howard

—

Francesca Cutolo

—

Bea Maria Salvador

—

Ahmed Ali Boutgoula

Esther's Interviewer

Marina Viro

—

Alberto Rosini

—

Mara Fronzi

—

David Sebasti

—

Enzo Samaritani

Girolamo's Caregiver

Giancarlo Fares

Leopold Essence

J. David Hinze

Emory Kitsworth

Mitchell Mullen

Ahmed

Houssem Benali

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Valentina Bernabei

—

Fabiola Cimminella

—

Nicole Biscaro