Theodore Templeton

Alec Baldwin

Tim Templeton

James Marsden

Carol Templeton(voice)

Eva Longoria

Tina Templeton/Boss Baby

Amy Sedaris

Dr. Armstrong

Jeff Goldblum

Tabitha

Ariana Greenblatt

Ted Templeton(voice)

Jimmy Kimmel

Janice Templeton

Lisa Kudrow

Wizzie (voice)

James McGrath

Nathan / Lead Baby Ninja (voice)

Raphael Alejandro

Meghan (voice)

Serenity Reign Brown

Jimbo (voice)

David Soren

Box Kid(voice)

Reyn Doi

Gracen Newton

The Triplets (voice)

Nicholas Gist

Creepy Girl

Molly K. Gray

Tim Templeton(voice)

Buddy Vedder

Story Bear (Connie) (voice)

James Ryan

Al Saif Alshad(voice)

Al Saif Alshad

Movie Patron (voice)

David P. Smith

Little Bo Peep Baby (voice)

Nova Reed

Creepy Girl (voice)

Molly K. Gray

'No' Girl (voice)

Ashlyn Lundahl

Glue Baby (voice)

Dave Needham

Dr. Tiffany Hamilton (voice)

Tom McGrath

Time Out Kid (voice)

Collin Erker

Baby Bouncer (voice)

Walt Dohrn

Acorn Center Computer (voice)

April Lawrence

Young Tim Voice-Over (voice)

Miles Bakshi

Pageant Mom 1 (voice)

Kristin Lowe

Pageant Mom 2 (voice)

Marjorie Cohn

Dreidel Kid (voice)

Connor Albrecht

Director

Tom McGrath