John

Jason Lee

Walter P. 'Duff' Duffy

Tom Green

Elaine Warner

Leslie Mann

Patty Plummer

Megan Mullally

Mr. Warner

Dennis Farina

Noreen

Tammy Blanchard

Mr. Cook

Richard Jenkins

David Loach

Chris Penn

Detective Charles

John C. McGinley

Uncle Jack

Seymour Cassel

Loach's Friend

Don Wilson

Butcher

Ken Magee

Liquor Store Clerk

Martin Starr

Duff's Mom

Mary Gillis

Fidio the Lawyer

Bruce McCulloch

Younger Noreen

Ashlynn Rose

Electrician

Nick Offerman

Aunt Jean

Lorna Scott

Electrician

Paul Feig

Grandma

Jeanette Miller

Uncle Dave

Bobby Harwell

Loach's Bandit

Thomas Rosales Jr.

Underage Kid

Gabe Laskin

Loach's Girlfriend

Steffiana De La Cruz

Underage Kid

Ashley Bishop

Lineup Man

Ernie Grunwald

Loretta

Pamela Gordon

Toy Store Manager

Marshall Manesh

Toy Store Salesperson

Tracy Ryan

Kid in Tree

Shane Wayton

Loach's Friend

Vinnie Curto

Loach's Bandit

Gilbert Rosales

Loach's Girlfriend

Steffiania Dela Cruz

Neighbor Lady

Channing Chase

Phone Sales

Brian Galyean

Phone Sales

Susan Solari

Phone Sales

Courtney Black

Noreen's Harvard Roommate

Terita Jackson