Robert Graysmith

Jake Gyllenhaal

Insp. David Toschi

Mark Ruffalo

Paul Avery

Robert Downey Jr.

Bill Armstrong

Anthony Edwards

Capt. Marty Lee

Dermot Mulroney

Melvin Belli

Brian Cox

Arthur Leigh Allen

John Carroll Lynch

Zodiac No. 1 & 2

Richmond Arquette

Jack Mulanax

Elias Koteas

Ken Narlow

Donal Logue

Zodiac No.3

Bob Stephenson

Zodiac No.4

John Lacy

Linda Ferrin

Clea Duvall

Melanie

Chloë Sevigny

Al Hyman

Ed Setrakian

Kathleen John

Ione Skye

Templeton Peck

John Getz

Jim Dunbar

Tom Verica

Charles Theiriot

John Terry

Cabbie Paul Stine

Charles Schneider

Bill Hamlet

Jim McNichols

Carol Fisher

Candy Clark

Cecelia Shepard

Pell James

Melvin Belli's Housekeeper

Doan Ly

Duffy Jennings

Adam Goldberg

Woman

Karina Logue

Mel Nicolai

Zach Grenier

Insp. Kracke

Joel Bissonnette

Mrs. Toschi

June Diane Raphael

Darlene Ferrin

Ciara Hughes

Don Cheney

John Hemphill

Young Mike Mageau

Lee Norris

Bob Vaughn

Charles Fleischer

Bryan Hartnell

Patrick Scott Lewis

Sandy Panzarella

Paul Schulze

Detective No.1

Adam Trese

Sherwood Morrill

Philip Baker Hall

Father

David Lee Smith

Copy Editor No.1

Thomas Kopache

Lab Tech Dagitz

Jason Wiles

Shorty

James Carraway

Mike Mageau

Jimmi Simpson

Riverside Captain

John Mahoney

John Allen

Matt Winston

Riverside Captain

John Mahon

Catherine Allen

Jules Bruff

Terry Pascoe

John Ennis

Police Commissioner

J. Patrick McCormack

Off. George Bawart

James LeGros

Mulanax's Secretary

Penny Wallace

Informant

F. Lennie Bleecher

Man on Marquee

Michel Francoeur

Copy Editor No.3

Barry Livingston

Copy Editor No.4

Christopher John Fields

Young David Graysmith

Jack Samson

David Graysmith

Micah Sauers

Aaron Graysmith

Zachary Sauers

Margot Graysmith

Jessica Baltutis

Patrolman Fouke

Peter Quartaroli

Patrolman Zelms

Geoff Callan

Truck Driver

Michael Hungerford

Society Woman

Anna Katarina

Informant (Hall of Justice A)

E.P. McKnight

Informant

Betty Murphy

Informant

Jeff Daniel Phillips

Informant

Shane Woodson

Informant #8

Cookie Crawford

Uniform Cop

Cassius Willis

Florence Douglas

Judith Drake

Prison Guard

Phoebe Holston

Pinole Foreman

Marty Lodge

Internal Affairs Agent #1

Cooper Thornton

Internal Affairs Agent #2

Cazimir Milostan

Kathleen Johns' baby

Charlotte Ferguson

Kathleen Johns' baby

Phoebe Ferguson

Kathleen Johns' baby

Kacey Malmsten

Kathleen Johns' baby

Karly Malmsten

Director

JD Cullum

Staff Editor

Stanley B. Herman

Distraught African American Male

Roy Lee Jones

Darlene Ferrin

Ciara Moriarty

Navy Project Leader

Michael Rose

DOD Project Leader

James Joseph O'Neil

FBI Codebreaker

Rod Damer

Donald Harden

John Sarno

Bettye Harden

Gloria Grant

Detective Roy

Brett Rickaby

Detective #2

Mark Bernier

Newscaster #2

Carter Evans

TV News Anchor

Bill Seward

Newscaster #4

Dave Nemeth

Anchorman #1

Ted Garcia

Interviewer #1

Greg Wolf

Reporter

Barry LeBrock