Barney Rubble / Dino / Mr. Spacely (voice)

Mel Blanc

George Jetson

George O'Hanlon

Elroy Jetson / W.C. Cogswell / Henry Orbit (voice)

Daws Butler

Fred Flintstone / Knight (voice)

Henry Corden

Astro / R.U.D.I / Mac / Announcer / Store Manager / Robot (voice)

Don Messick

Jane Jetson (voice)

Penny Singleton

Iggy (voice)

Jon Bauman

Turk Tarpit (voice)

Hamilton Camp

Judy Jetson / Female Computer (voice)

Janet Waldo

Betty Rubble / Jet Rivers / Investor / Panelist / Harem Girl (as Julie Dees) (voice)

Julie McWhirter

Wilma Flintstone / Rosie / Mrs. Spacely (voice)

Jean Vander Pyl

Mr. Slate / Moderator / Investor / Poker Player (voice)

John Stephenson

Didi (voice)

Brenda Vaccaro

Dan Rathmoon / Johnny / Mr. Goldbrick (voice)

Frank Welker

(voice)

Patric Zimmerman