Debbie

Leslie Mann

Pete

Paul Rudd

Oliver

John Lithgow

Desi

Megan Fox

Larry

Albert Brooks

Ronnie

Chris O'Dowd

Jason

Jason Segel

Catherine

Melissa McCarthy

Joseph

Ryan Lee

Charlotte

Iris Apatow

Sadie

Maude Apatow

Barry

Robert Smigel

Jodi

Charlyne Yi

Barb

Annie Mumolo

Male Boutique Customer

Hugh Fink

Himself

Graham Parker

Graham Parker Solo Band

Tom Freund

Older Pregnant Parent

D.A. Sandoval

School Playdate Parent

Megan Grano

School Playdate Child

Mackenzie Aladjem

Charlotte's Teacher

Tom Yi

Grandma Molly

Molly Shad

Accountant

Michael Ian Black

Cat

Lena Dunham

Jewish Journal Reporter

David Wild

Mammogram Technician

Barb Hernandez

Pete's Doctor

Tom Everett

Dr. Pellegrino

Tim Bagley

Colonoscopy Technician

Damon Gupton

Dentist

Dan Bakkedahl

Gyno Nurse

Rebekah Johnson

Gyno Nurse

Erica Vittina Phillips

Triplet

Jack Metcalf

Triplet

Travis Metcalf

Triplet

Bradley Metcalf

Claire

Lisa Darr

Room Service Waiter

Johnny Pemberton

Eastern Doctor

Sam Dissanayake

Realtor

Tatum O'Neal

Wendy

Ava Sambora

Sadie's Set-Pain

Nyla Durdin

Flirty Hockey Player

Wyatt Russell

Hockey Player

Philip Burke

Himself

R. Matt Carle

Himself

Ian Laperrière

Himself

James F. Van Riemsdyk

Himself

Scott Wesley Hartnell

Himself

Billie Joe Armstrong

Vice Principal Laviani

Joanne Baron

Obnoxious Teenager in SUV

Spencer Daniels

Obnoxious Teenager in SUV

Charlotte Townsend

Man in Range Rover

Phil Hendrie

ER Nurse

Nicol Paone

Himself

Ryan Adams

Director

Judd Apatow