Sheldon

Iain Armitage

Mary

Zoe Perry

George Sr.

Lance Barber

Meemaw

Annie Potts

Georgie

Montana Jordan

Missy

Raegan Revord

Adult Sheldon

Jim Parsons

Herschel

Billy Gardell

Mr. Lundy

Jason Alexander

Dr. John Sturgis

Wallace Shawn

Veronica

Isabel May

Dr. Sandra Thorpe

Amy Farrington

Mr. Gilford

Barry Corbin

Dr. Linkletter

Ed Begley Jr.

Principal Petersen

Rex Linn

Paige

Mckenna Grace

Pastor Jeff

Matt Hobby

Tam

Ryan Phuong

Bruce

Jonney Ahmanson

Trang Nguyen

VyVy Nguyen

Dr. Edward Pilson

Wallace Langham

Diane

Pam Cook

Peg

Nancy Linehan Charles

Nurse Robinson

Vernee Watson

Clint Watson

Tim Griffin

Barry

Josh Cooke

Mr. Givens

Brian Stepanek

Linda

Andrea Anders

Tommy

Ryan Cargill

Mai Nguyen

Cheyenne Nguyen

Billy Sparks

Wyatt McClure

Ms. Ingram

Danielle Pinnock

Kim-Ly Nguyen

Angelina Nguyen

Teresa

Yennifer Behrens

Brenda Sparks

Melissa Peterman

Dr. Gilbert

Wayne Wilderson

Ms. Hutchins

Sarah Baker

Alf

Paul Fusco

Marcus

Rodney J. Hobbs

Hank

Josh Latzer

Erica

Ella Anderson

Assistant Coach Wilkins

Doc Farrow

Ms. Macelroy

Valerie Mahaffey

Ricky

Mauricio Lara

Dr. Lee

Susan Chuang

Glenn

Chris Wylde

Wyatt McClure

Billy Sparks

Dealer

Christopher Carrington

Mikey

Alexander Arzu

Russian Dad

Zoran Radanovich

Fred Murphy

Adam Kulbersh

Paula

Livia Treviño

Anchor

Katherine Von Till

Stan

Alex Staggs

Officer Robin

Mary Grill

Elliot

Bryce McBratnie

Tim

Ivan Mallon

Jason

Forrest Deal

Nell Cavanaugh

Isabella Coben

Shawn

Alfred Woodley

Gary

Chris Flanders

Francine

Megan Park

Felicia

Melanie Haynes

DMV Employee

Kevin D'Arcy

Japanese Dad

Kirt Kishita

Leslie

Sara Sanderson

Derek

Nick Alvarez

Bryan

Jordan Leer

Melissa

Dale Raoul

Mayor Harrison

Robert Clotworthy

Paramedic

John Eddins

Daisy

Kiva Jump

Waitress

Heather Olt

Five-Year-Old Sheldon

Parker Dailey

Agent 1

Franco Vega

Greg

Michael C. Alexander

Pete

Travis Guba

Judy

Hilda Boulware

Shelby

Daniele Lawson

Abby

Annelise Grace

Actor 1

Kirk Bovill

Selena

Zuleyka Silver

Shopper 1

Tiffany Jeneen

Actor 2

Shane Blades

Shopper 2

Jay Brian Winnick

Jared

Jack Seaver McDonald

Actress

Joy Jacobson