Director Phil Coulson/Sarge
Clark Gregg
Agent Melinda May
Ming-Na Wen
Daisy Johnson
Chloe Bennet
Leo Fitz
Iain De Caestecker
Agent Jemma Simmons
Elizabeth Henstridge
Alphonso "Mack" Mackenzie
Henry Simmons
Elena "Yo-Yo" Rodriguez
Natalia Cordova-Buckley
Deke Shaw
Jeff Ward
Grant Ward / Hive
Brett Dalton
Guest Star
Joel Stoffer
Guest Star
Jolene Anderson
Guest Star
Tamara Taylor
Guest Star
Thomas E. Sullivan
Guest Star
Dichen Lachman
Guest Star
Austin Basis
Guest Star
Darren Barnet
Guest Star
Julian Acosta
Guest Star
Larry Clarke
Guest Star
Ryan Donowho
Guest Star
Tobias Jelinek
Guest Star
Joe Reegan
Lance Hunter
Nick Blood
Guest Star
Dianne Doan
Guest Star
Michael Gaston
Guest Star
Nora Zehetner
Guest Star
James Paxton
Bobbi Morse
Adrianne Palicki
Guest Star
Neal Bledsoe
Guest Star
Briana Venskus
Guest Star
Paulina Bugembe
Guest Star
Patton Oswalt
Guest Star
Stephen Bishop
Guest Star
Greg Finley
Lincoln Campbell
Luke Mitchell
Guest Star
Cameron Palatas
Guest Star
Maximilian Osinski
Guest Star
Tipper Newton
Guest Star
Dawan Owens
Holden Radcliffe
John Hannah
Guest Star
Bill Cobbs
Guest Star
Luke Baines
Guest Star
Sedale Threatt Jr.
Guest Star
Enver Gjokaj
Guest Star
Coy Stewart
Guest Star
Byron Mann
Enoch
Joel Stoffer
Guest Star
Patrick Warburton
Robbie Reyes / Ghost Rider
Gabriel Luna
Glenn Talbot / Graviton
Adrian Pasdar
Guest Star
Shakira Barrera
Aida / Agnes Kitworth
Mallory Jansen
Antoine Triplett
B.J. Britt
Ron Glass
Raina
Ruth Negga
Cal / The Doctor / Skye's Father
Kyle MacLachlan
General Hale
Catherine Dent
Mike Peterson / Deathlok
J. August Richards
Deke Shaw
Jeff Ward
Andrew Garner
Blair Underwood
Sunil Bakshi
Simon Kassianides
Gordon
Jamie Harris
Stern Woman
Mary Eileen O'Donnell
Carl Creel
Brian Patrick Wade
Agent Weaver
Christine Adams
Anton Ivanov
Zach McGowan
Kasius
Dominic Rains
Sinara
Florence Faivre
Ian Quinn
David Conrad
Daniel Whitehall
Reed Diamond
Izel
Karolina Wydra
Kara Palamas / Agent 33
Maya Stojan
Rosalind Price
Constance Zimmer
Snowflake
Brooke Williams
JT James / Hellfire
Axle Whitehead
John Garrett
Bill Paxton
Agent Anderson
Alexander Wraith
Waiter
Amos Glick
Bandleader
Martin Blasick
Qovas
Peter Mensah
Abel
Ryan Gray
Jaco
Winston James Francis
Lash
Matthew Willig
Joey Gutierrez
Juan Pablo Raba
Carla Talbot
Raquel Gardner
Robert Gonzales
Edward James Olmos
Agent Oliver
Mark Allan Stewart
Luther Banks
Andrew Howard
Candice Lee
Shontae Saldana
Werner von Strucker
Spencer Treat Clark
Tess
Eve Harlow
Malachi
Christopher James Baker
Pax
Matt O'Leary
Marcus Benson
Barry Shabaka Henley