Sarge

Clark Gregg

Agent Melinda May

Ming-Na Wen

Daisy Johnson

Chloe Bennet

Leo Fitz

Iain De Caestecker

Agent Jemma Simmons

Elizabeth Henstridge

Agent Alphonso "Mack" MacKenzie

Henry Simmons

Elena "Yo-Yo" Rodriguez

Natalia Cordova-Buckley

Deke Shaw

Jeff Ward

Guest Star

Maximilian Osinski

Grant Ward / Hive

Brett Dalton

Guest Star

Joel Stoffer

Guest Star

Briana Venskus

Enoch

Joel Stoffer

Guest Star

Barry Shabaka Henley

Guest Star

Lucas Bryant

Guest Star

Karolina Wydra

Guest Star

Anthony Michael Hall

Guest Star

Winston James Francis

Guest Star

Maurissa Tancharoen

Lance Hunter

Nick Blood

Guest Star

Brooke Williams

Guest Star

Robb Derringer

Guest Star

Matt O'Leary

Bobbi Morse

Adrianne Palicki

Guest Star

Coy Stewart

Guest Star

Christopher James Baker

Guest Star

Paul Telfer

Lincoln Campbell

Luke Mitchell

Guest Star

Jan Uddin

Holden Radcliffe

John Hannah

Guest Star

Sola Bamis

Guest Star

Sherri Saum

Guest Star

Shainu Bala

Guest Star

Glenn Keogh

Robbie Reyes / Ghost Rider

Gabriel Luna

Guest Star

Levi Meaden

Glenn Talbot / Graviton

Adrian Pasdar

Aida / Agnes Kitworth

Mallory Jansen

Antoine Triplett

B.J. Britt

Raina

Ruth Negga

Cal / The Doctor / Skye's Father

Kyle MacLachlan

Jiaying

Dichen Lachman

Billy Koenig / Sam Koenig / Ernest Koenig

Patton Oswalt

General Hale

Catherine Dent

Mike Peterson / Deathlok

J. August Richards

Daniel Sousa

Enver Gjokaj

Andrew Garner

Blair Underwood

Sunil Bakshi

Simon Kassianides

Gordon

Jamie Harris

Nathaniel Malick

Thomas E. Sullivan

Carl Creel

Brian Patrick Wade

Ron Glass

Agent Weaver

Christine Adams

Anton Ivanov

Zach McGowan

Kasius

Dominic Rains

Sinara

Florence Faivre

Ian Quinn

David Conrad

Daniel Whitehall

Reed Diamond

Kara Palamas / Agent 33

Maya Stojan

Quinjet Pilot

Geri-Nikole Love

l'agent Julian

Matthew Law

Rosalind Price

Constance Zimmer

l'agent More

Miguel A. Lopez

Runco

Adam Burnette

JT James / Hellfire

Axle Whitehead

le directeur du musée

Zack Whyel

John Garrett

Bill Paxton

Agent Anderson

Alexander Wraith

Qovas

Peter Mensah

Luke / William Dole

Tobias Jelinek

Lash

Matthew Willig

Joey Gutierrez

Juan Pablo Raba

Carla Talbot

Raquel Gardner

Robert Gonzales

Edward James Olmos

Agent Oliver

Mark Allan Stewart

Luther Banks

Andrew Howard

Tinker

Xavier Jimenez-March

Candice Lee

Shontae Saldana

Werner von Strucker

Spencer Treat Clark

Tess

Eve Harlow

Sibyl

Tamara Taylor

Kora

Dianne Doan

Director

Clark Gregg

Director

Garry A. Brown

Director

Lou Diamond Phillips

Director

Jennifer Phang

Director

Kevin Tancharoen