Master Chief Petty Officer John-117

Pablo Schreiber

Dr. Catherine Halsey

Natascha McElhone

Cortana (voice)

Jen Taylor

Soren-066

Bokeem Woodbine

Spartan Riz-028

Natasha Culzac

Admiral Margaret Parangosky

Shabana Azmi

le docteur Miranda Keyes

Olive Gray

Spartan Vannak-134

Bentley Kalu

Kwan Ha

Yerin Ha

Spartan Kai-125

Kate Kennedy

Makee

Charlie Murphy

Laera

Fiona O'Shaughnessy

Captain Jacob Keyes

Danny Sapani

Vinsher Grath

Burn Gorman

Dr. Adun Saly

Ryan McParland

Kessler

Tylan Bailey

James Ackerson

Joseph Morgan

Cortana

Christina Bennington

Corporal Talia Perez

Cristina Rodlo

Arbiter Var 'Gatanai

Viktor Åkerblom-Nilsson

Young John

Casper Knopf

Hierarch Mercy (voice)

Julian Bleach

The Mother

Olwen Fouéré

John's Mother

Sarah Ridgeway

John's Father

Duncan Pow

Kaidon

Jamie Beamish

Ops Tech / Ops Tech Pereira / Sangheili Guard

Hans Peterson

Hierarch Regret (voice)

Hilton McRae

MP Malya

Claudius Peters

Hierarch Truth (voice)

Karl Johnson

Djanka

Nneka Okoye

Carina

Juliette Motamed

Flight Tech Doan

Chan Woo Lim

Castor

David Crowley

Virgil

Iliász Shweirif

Professor

Ian Pirie

Antares

Ivanno Jeremiah

Manuela Perez

Maria Luisa Costa

Erika Wize

Gabrielle Glaister

Louis-036

Marvin 'Krondon' Jones III

Ruben

Sky Yang

Danilo

Christian Ochoa

Captain Briggs

Anna Koval

Lt Mullins

Dani Klupsch

Tech Smith

Ailsa Davidson

Tech Jones

Tom Gaskin

Natasha McElhone