Dr. Ephraim Goodweather

Corey Stoll

Professor Abraham Setrakian

David Bradley

Dr. Nora Martinez

Mia Maestro

Vasiliy Fet

Kevin Durand

Jim Kent

Sean Astin

Augustin "Gus" Elizalde

Miguel Gomez

Kelly Goodweather

Natalie Brown

Thomas Eichhorst

Richard Sammel

Eldritch Palmer

Jonathan Hyde

Zach Goodweather

Max Charles

The Master / Jusef Sardu

Robert Maillet

Dutch Velders

Ruta Gedmintas

Gabriel Bolivar / The Master

Jack Kesy

Zack Goodweather

Ben Hyland

The Master (voice)

Robin Atkin Downes

Mr. Quinlan

Rupert Penry-Jones

Crispin

Francis Capra

Mr. Fitzwilliam

Roger Cross*

Joan Luss

Leslie Hope

Ruby Wain

Regina King

Justine Feraldo

Samantha Mathis

Sylvia Kent

Melanie Merkosky*

Matt Sayles

Drew Nelson

Strigoi

Anthony Grant Lake

Reggie Fitzwilliam

Roger Cross

Angel Guzman Hurtado

Joaquín Cosío

Alonso Creem

Jamie Hector

Sanjay Desai

Cas Anvar

Coco Marchand

Lizzie Brocheré

Frank Kowalski

Paulino Nunes

Roman

K. C. Collins

Marcus

Dewshane Williams

Dr. Everett Barnes

Daniel Kash

Guadalupe Elizalde

Adriana Barraza

Abraham (Young Setrakian)

Jim Watson

Mariela Martinez

Anne Betancourt

Mayor George Lyle

Ron Canada

Street Mongrel

Troy James

Alex Green

Angel Parker

Abby

Jocelyn Hudon

Ansel Barbour

Nikolai Witschl

The Ancient

Doug Jones

Director

Vincenzo Natali

Director

Guillermo Del Toro

Director

J. Miles Dale

Director

Peter Weller

Director

T.J. Scott

Director

Kevin Dowling