Young Sheldon Cooper

Iain Armitage

Mary Cooper

Zoe Perry

George Cooper

Lance Barber

Connie Tucker

Annie Potts

Georgie Cooper

Montana Jordan

Missy Cooper

Raegan Revord

Sheldon Cooper (voice)

Jim Parsons

Victoria MacElroy

Valerie Mahaffey

John Sturgis

Wallace Shawn

Principal Petersen

Rex Linn

Ms. Fenley

Melissa Tang

Pastor Hodgkins

Matt Hobby

Dale Ballard

Craig T. Nelson

Billy Sparks

Wyatt McClure

Evelyn Ingram

Danielle Pinnock

Mandy McAllister

Emily Osment

Hubert Givens

Brian Stepanek

Coach Bergdoff

Doc Farrow

Woman at Church

Marcia Ann Burrs

Grant Linkletter

Ed Begley Jr.

Stinson

Christian Garcia

Brenda Sparks

Melissa Peterman

Tam Nguyen

Ryan Phuong

Linda Hagemeyer

Wendie Malick

Peg

Nancy Linehan Charles

Sheryl Hutchins

Sarah Baker

Kid Spectator

Allaunah Chacon

Audrey McAllister

Rachel Bay Jones

Football Player

T.J. Shaw

Jim McAllister

Will Sasso

Paige Swanson

Mckenna Grace

John Debney

Jana Boggs

Ava Allan

Veronica Duncan

Isabel May

Chuck Lorre

Steven Molaro

Wade

Grady Lee Richmond

Timothy Marx

Rob

Dan Byrd

Todd Spiewak

Kimberly / Local Newscaster

Katherine Von Till

June

Reba McEntire

Professor Proton

Bob Newhart

Linda Swanson

Andrea Anders

Stinson

Christian Alexander Garcia

Robin

Mary Grill

Gene Lundy

Jason Alexander

Herschel Sparks

Billy Gardell

Derek

Nick Alvarez

Sandy

Caleigh Kilpatrick

Student

Nicole Bosworth