Young Sheldon Cooper

Iain Armitage

Mary Cooper

Zoe Perry

George Cooper

Lance Barber

Connie Tucker

Annie Potts

Georgie Cooper

Montana Jordan

Missy Cooper

Raegan Revord

Dr. John Sturgis

Wallace Shawn

Sheldon Cooper (voice)

Jim Parsons

Paige Swanson

Mckenna Grace

Linda Swanson

Andrea Anders

Barry

Josh Cooke

Jeff Difford

Matt Hobby

Erica

Ella Anderson

Dale Ballard

Craig T. Nelson

Billy Sparks

Wyatt McClure

Mandy McAllister

Emily Osment

Wayne Wilkins

Doc Farrow

Grant Linkletter

Ed Begley Jr.

Brenda Sparks

Melissa Peterman

Tam Nguyen

Ryan Phuong

Tom Petersen

Rex Linn

Hubert Givens

Brian Stepanek

Linda Hagemeyer

Wendie Malick

Peg

Nancy Linehan Charles

Evelyn Ingram

Danielle Pinnock

Victoria MacElroy

Valerie Mahaffey

Sheryl Hutchins

Sarah Baker

Audrey McAllister

Rachel Bay Jones

Jim McAllister

Will Sasso

Jana Boggs

Ava Allan

Veronica Duncan

Isabel May

Wade

Grady Lee Richmond

Rob

Dan Byrd

Kimberly / Local Newscaster

Katherine Von Till

June

Reba McEntire

Robin

Mary Grill

Gene Lundy

Jason Alexander

Herschel Sparks

Billy Gardell

Derek

Nick Alvarez