Ned

Lee Pace

Charlotte"Chuck" Charles

Anna Friel

Emerson Cod

Chi McBride

Vivian Charles

Ellen Greene

Lily Charles

Swoosie Kurtz

Olive Snook

Kristin Chenoweth

Young Ned

Field Cate

Narrator (voice)

Jim Dale

Guest Star

Paul Reubens

Guest Star

Dash Mihok

Guest Star

Patrick Fabian

Guest Star

Molly Shannon

Bernard Slaybaugh

Jonathan Mangum

Guest Star

Hamish Linklater

Guest Star

Mike White

Guest Star

Vince Cefalu

Guest Star

Colby Paul

Young Chuck

Sammi Hanratty

Guest Star

Christopher Sieber

Guest Star

Eddie Shin

Guest Star

Karly Rothenberg

Guest Star

Riki Lindhome

Guest Star

Sy Richardson

Guest Star

Barbara Barrie

Guest Star

Julia Campbell

Guest Star

Audrey Wasilewski

Guest Star

Christopher Neiman

Guest Star

Joel McHale

Dwight Dixon

Stephen Root

Guest Star

Tim Conlon

Guest Star

Patrick Breen

Guest Star

Carlos Alazraqui

Guest Star

E.J. Callahan

Guest Star

Brad Grunberg

Guest Star

Sam Pancake

Guest Star

Grant Shaud

Guest Star

Lydia Look

Guest Star

Omar Avila

Guest Star

Raúl Esparza

Guest Star

Sarah Jayne Jensen

Guest Star

Leyna Nguyen

Guest Star

Pamela Kosh

Guest Star

Michael Merton

Guest Star

Ralph P. Martin

Eugene Mulchandani

Nicholas Khayyat

Guest Star

Matt Braunger

Guest Star

Terry Anzur

Guest Star

Jessica Lundy

Mother Superior

Diana Scarwid

Guest Star

Taji Coleman

Guest Star

Julie Wittner

Guest Star

Jeff Marlow

Guest Star

Jayma Mays

Guest Star

Jenny Wade

Ned's Mother

Tina Gloss

Guest Star

Lawrence Schatz

Ned's Father

Jon Eric Price

Guest Star

Reginald Veneziano

Guest Star

Greg Suddeth

Delivery Boy

Victor Z. Isaac

Guest Star

Howard Mann

Guest Star

Abbe Meryl

Simone Hundin

Christine Adams

Guest Star

Alex Endeshaw

Randy Mann

David Arquette

Guest Star

Mark Harelik

Guest Star

Michael Cornacchia

Guest Star

Ted Garcia

Guest Star

Allan Graf

Guest Star

Kristin Dos Santos

Guest Star

Dan Glenn

Guest Star

Wesley Harris

Guest Star

Joe Don Harris

Guest Star

Geraud Moncure

Guest Star

Tammy Dahlstrom

Guest Star

David Trice

Guest Star

Ed Brigadier

Ingmar Todd

Daeg Faerch

Guest Star

Murray Gershenz