Jigsaw

Tobin Bell

Hoffman

Costas Mandylor

Agent Straum

Scott Patterson

Jill

Betsy Russell

Rigg

Lyriq Bent

Agent Perez

Athena Karkanis

Art

Justin Louis

Lamanna

Simon Reynolds

Eric Mathews

Donnie Wahlberg

Fisk

Mike Realba

Jeff

Angus Macfadyen

Ivan

Marty Adams

Corbett

Niamh Wilson

Amanda

Shawnee Smith

Lynn

Bahar Soomekh

Brenda

Sarain Boylan

Cecil

Billy Otis

Kerry

Dina Meyer

Dr. Heffner

James Van Patten

Trevor

Kevin Rushton

Pathologist

David Boyce

Vagrant

Julian Richings

SWAT Pete

Kelly Jones

Tracy

Ingrid Hart

Morgan

Janet Land

Rex

Ron Lea

Crime Scene Photographer

Joanne Boland

Lab Technician

Zoe Heath

Young Cop

Bill Vibert

Matt

Eric Gores

Derek

Devon Bostick

Gus

Tony Nappo

Addison Corday

Emmanuelle Vaugier

Michael Marks

Noam Jenkins

Paul Leahy

Mike Butters

Troy

J. LaRose

The Man

Oren Koules

Young Girl

Alison Luther

Nurse Deborah

Kim Roberts

Dr. Steve

David Webster

Nurse Patti

Sandra Manson

Additional Voice Talent (voice)

Shauna Black

Additional Voice Talent (voice)

Darrell Dennis

Additional Voice Talent (voice)

Tracey Ferencz

Additional Voice Talent (voice)

Catherine Fitch

Additional Voice Talent (voice)

Christopher Marren

Additional Voice Talent (voice)

Christopher Morris

Additional Voice Talent (voice)

Geoffrey Pounsett

Voice

Chris Marren

Darren Lynn