Jigsaw

Tobin Bell

Hoffman

Costas Mandylor

Jill

Betsy Russell

Erickson

Mark Rolston

William

Peter Outerbridge

Amanda

Shawnee Smith

Agent Perez

Athena Karkanis

Pamela Jenkins

Samantha Lemole

Debbie

Caroline Cave

Harold

George Newbern

Simone

Tanedra Howard

Dave

Darius McCrary

Eddie

Marty Moreau

Allen

Shawn Ahmed

Tara

Shauna MacDonald

Brent

Devon Bostick

Addy

Janelle Hutchison

Janitor

Gerry Mendicino

Tara

Shauna Macdonald

Josh

Shawn Mathieson

Gena

Melanie Scrofano

Shelby

Karen Cliche

Aaron

James Gilbert

Emily

Larissa Gomes

Newscaster

Dan Duran

Coroner

James Van Patten

Female Addict

Jon Mack

Cecil

Billy Otis

Male Addict

François Sagat

Clinic Nurse

Elle Downs

Irate Clinic Woman

Tenika Davis

Security Guard

Karl Campbell

Sachi

Ginger Busch

Female Officer

Jessie Rusu

Tim

Mpho Koaho

Sachi

Ginger Ruriko Busch

Additional Voice Talent

Chris Owens

Shawnee

Additional Voice Talent

Vickie Papavs

Additional Voice Talent

Catherine Rix

Additional Voice Talent

John Watson

John / Jigsaw

Tom Bell