Riley/Huey
Regina King
Grandad
John Witherspoon
Voice
J.D. Witherspoon
Jazmine
Gabby Soleil
Tom DuBois
Cedric Yarbrough*
Tom Dubois (voice)
Cedric Yarbrough
Sarah Dubois (voice)
Jill Talley
Uncle Ruckus (voice)
Gary Anthony Williams
Kim Kardashian (voice) / Loyal White Woman (voice) / Siri (voice)
Grey DeLisle
Ed Wuncler
Ed Asner
Boss Willona (voice) / Geraldine (voice)
Jenifer Lewis
Pretty Boy Flizzy (voice)
Michael B. Jordan
Cristal (voice)
Tiffany Thomas
Jigme (voice)
Dante Basco
Ebony Brown
Gina Torres
Sturdy Harris (voice)
Dennis Haysbert