Archie Andrews
K.J. Apa
Betty Cooper
Lili Reinhart
Veronica Lodge
Camila Mendes
Jughead Jones
Cole Sprouse
Geraldine Grundy
Sarah Habel
Cheryl Blossom
Madelaine Petsch
Hermione Lodge / Apollonia Gomez / Hermione Lodge (voice)
Marisol Nichols
Alice Cooper
Madchen Amick
F.P. Jones
Skeet Ulrich
Kevin Keller
Casey Cott
Hiram Lodge
Mark Consuelos
Fred Andrews
Luke Perry
Toni Topaz
Vanessa Morgan
Bret Weston Wallis
Sean Depner
Josie Mccoy
Ashleigh Murray
Reggie Mantle
Charles Melton
Donna Sweett
Sarah Desjardins
Reggie Mantle / Reggie Prime
Ross Butler
Dr. Freiderich Werthers / Francis J. Dupont / Dr. Fredreich Werthers
Malcolm Stewart
Mrs. Burble
Gina Torres
Fangs Fogarty
Drew Tanner
Abuelita
Ana Mercedes
Katy Keene
Lucy Hale
Holden Honey
Kerr Smith
Guest Star
Shannen Doherty
Mary Andrews
Molly Ringwald
Dodger Dickenson
Juan Riedinger
Munroe 'Mad Dog' Moore
Eli Goree
Ms. Wright
Penelope Ann Miller
Mr. Chipping
Sam Witwer
Uncle Frank
Ryan Robbins
Edgar Evernever
Chad Michael Murray
Charles Smith
Wyatt Nash
Tom Keller / Mayor Keller
Martin Cummins
Ms. Appleyard
Emily Tennant
Forsythe Pendleton Jones I
Timothy Webber
Gladys Jones
Gina Gershon
Jellybean "JB" Jones
Trinity Likins
Nick St. Clair
Graham Phillips
Pop Tate
Alvin Sanders
Penelope Blossom
Nathalie Boltt
Nana Rose Blossom
Barbara Wallace
Hal Cooper
Lochlyn Munro
Tabitha Tate
Erinn Westbrook
Waldo Weatherbee / Principal Waldo Weatherbee
Peter Bryant
Frank Andrews
Ryan Robbins
Sweet Pea
Jordan Connor
Moose Mason
Cody Kearsley
Polly Cooper
Tiera Skovbye
Clifford Blossom / Mayor Clifford Blossom / Claudius Blossom
Barclay Hope
Dr. Curdle Jr.
Nikolai Witschl
Sierra McCoy
Robin Givens
Ethel Muggs / Rivervale Ethel
Shannon Purser
Evelyn Evernever
Zoé De Grand Maison
Smithers
Tom McBeath
Jason Blossom / Clifford Blossom
Trevor Stines
Principal Featherhead / Warden Norton
William MacDonald
Doris Bell
Marion Eisman
Julian Blossom
Nicholas Barasch
Clay Walker
Karl Walcott
Dilton Doiley
Daniel Yang
Ben Button / Ben / Snack Bar Guy
Moses Thiessen
Britta Beach / Abigail Blossom / Rivervale Britta
Kyra Leroux
Valerie Brown
Hayley Law
Percival Pickens / Sheriff Perkins / Perry Pierce
Christopher O'Shea
Melody Valentine
Asha Bromfield
Joan Berkeley
Doralynn Mui
Midge Klump
Abby Ross
Chic
Hart Denton
Johnathan
Alex Barima
Janet Weiss / Ms. Weiss
Alison Araya
Penny Peabody
Brit Morgan
Sister Woodhouse / Sister Hoodhouse
Beverley Breuer
Hermosa Lodge
Mishel Prada
Joaquin DeSantos
Rob Raco
Peaches 'N Cream
Bernadette Beck
Midge Klump / Midge
Emilija Baranac
Dagwood / Dogwood
Bentley Storteboom
Glen Scot / Patchwork Glen
Greyston Holt
Al Fieldstone
Garry Chalk
Michael Minetta / Sheriff Minetta
Henderson Wade
Juniper
Alix West Lefler
Eric Jackson
Sommer Carbuccia
Elio
Julian Haig
Dilton Doiley / Daryl Doiley
Major Curda
Young Betty Cooper / Young Betty / Li'l Polly
Hannah Bos
Heather
Caroline Day
Andre
Stephan Miers
Chadwick 'Chad' Gekko
Chris Mason
Toby
Jordan Robinson
Samm Pansky
Peter Kelamis
Marty Mantle
Matthew Yang King
Twyla Twyst
Alaina Huffman
Baby Anthony
Ace Rudy Allan Carter
Mrs. Thornton
Frances Flanagan
Ginger Lopez
Caitlin Mitchell-Markovitch
Floyd Clayton
Colin Lawrence
Chuck Clayton
Jordan Calloway
Laura
Brittany-Ellen Willacy
Bernie Burstein / Dealer
Jesse Goldwater
Carlos
Alexander Soto
Tina Patel
Olivia Ryan Stern
Minerva Marble
Adeline Rudolph
Aunt Cricket
Arabella Bushnell
Arthur Adams
John Behlmann
Kurtz
Jonathan Whitesell
Vic
Bruce Blain
Eddie
Ajay Friese
Malcolm
Marlon Kazadi
Delores
Sheila Tyson
Darla Dickenson
Azura Skye
The Milkman / Quiz Show Host
Matty Finochio
Agent Marsha Lin
Quinnie Vu
Agent Jillian Drake
Sophia Tatum
Lizzo
Alyssa Wapanatâhk