Angus "Mac" MacGyver

Lucas Till

Jack Dalton

George Eads

Riley Davis

Tristin Mays

Wilt Bozer

Justin Hires

Matty Webber

Meredith Eaton

Desiree "Desi" Nguyen

Levy Tran

Samantha Cage

Isabel Lucas

Russ Taylor

Henry Ian Cusick

Jill Morgan

Kate Bond

Oversight

Tate Donovan

Murdoc

David Dastmalchian

Martin Bishop

Joshua Leonard

Robot (voice)

Nicholas Guest

Russian Bear

Michael Foster

Elwood

William Baldwin

Billy Colton

Lance Gross

Journalist

Valerie Jane Parker

Scarlett

Amber Skye Noyes

Yakuza Enforcer

Toshiji Takeshima

Firefighter

Scott Lomas

Charlie Robinson

Emerson Brooks

Arms Dealer Party Guest

Felicia M. Reyes

Parker

Alexandra Grey

Nikki Carpenter

Tracy Spiridakos

Nasha

Sibongile Mlambo

Sergei / Russian Guard #2 / Silver Wall Security Guard

Andre Pushkin

Sandrine Holt

Reign Edwards