Square-jawed comedic actor Bill Hader emerged as an onscreen presence in the mid- to late 2000s, both as a regular player on the hallowed Saturday Night Live and as an occasional performer in movies such as the animated Doogal (2004) and the Owen Wilson vehicle You, Me and Dupree (2006). Hader rose to higher billing with his guffaw-inducing turn in the frat-boy comedy Superbad (2007), playing a seriously irresponsible cop and the partnered with Seth Rogen. He was the brother to Jason Segel's character in Forgetting Sarah Marshall, had a brief but memorable cameo right at the beginning of Pineapple Express, and played a sycophantic assistant to Tom Cruise's monstrous Hollywood mogul in Tropic Thunder, all in 2008. The next year he had a huge hit voicing a character in the animated smash Cloudy With a Chance of Meatballs, and earned good reviews for his work in Adventureland. He appeared in the sci-fi comedy Paul in 2011.

Hader continued to appear in supporting and cameo roles in films, appearing in an impressive nine films in 2013 (many of them voice roles, including Monsters University and reprising his role in Cloudy with a Chance of Meatballs 2), before annoucing he was leaving Saturday Night Live. Once leaving SNL, he stretched his acting legs by starring opposite Kristen Wiig in the dramedy The Skeleton Twins in 2014.