Mahershala Ali

Mark Grayson / Invincible (voice)

Steven Yeun

Nolan Grayson / Omni-Man (voice)

J.K. Simmons

General Kregg (voice) / Damien Darkblood (voice) / General Kregg

Clancy Brown

Debbie Grayson

Sandra Oh

Nicole Byer

Allen the Alien

Seth Rogen

Jeffrey Donovan

Cecil Stedman

Walton Goggins

Art Rosebaum

Mark Hamill

Jon Hamm

Shrinking Rae / Monster Girl / Olga (voice)

Grey DeLisle

Rex (voice) / Rex / Zombie #2 (voice)

Jason Mantzoukas

Djimon Hounsou

Amber Bennett

Zazie Beetz

Eve (voice) / Eve / College Girl (voice)

Gillian Jacobs

Ezra Miller

Fightmaster & Dropkick

Mae Whitman

William (voice) / Everest Climber (voice)

Andrew Rannells

Oliver Grayson

Max Burkholder

Donald (voice) / Donald / Doc Seismic (voice)

Chris Diamantopoulos

Black Samson (voice) / Black Samson / Astronaut (voice)

Khary Payton

Battle Beast

Michael Dorn

Mauler 1 / Mauler 2 (voice) / Mauler 2

Kevin Michael Richardson

Immortal / Rudy (voice) / Rudy

Ross Marquand

Kate Cha/Dupli-Kate

Melise

Robot (voice) / Robot / Robot Life Pod (voice)

Zachary Quinto

Additional Voices (voice)

Robert Kesselman

Additional Voices (voice)

Dan Navarro

Additional Voices (voice)

Ami Shukla

Additional Voices (voice) / Bridget

Nyima Funk

Killcannon / Captain / Paramedic (voice)

Fred Tatasciore

Bulletproof (voice) / Bulletproof / Dinosaur #2

Jay Pharoah

Angstrom Levy (voice) / Angstrom Levy / Angstrom #646 (voice)

Sterling K. Brown

Shapesmith / Rus / Punk Thug (voice)

Ben Schwartz

Paul (voice)

Cliff Curtis

King Lizard (voice)

Scoot McNairy

Newscaster / Umpire / Scientist (voice)

Gary Anthony Williams

Principal / Dean Winslow (voice) / Principal Winslow

Reginald VelJohnson

April (voice)

Calista Flockhart

Director

Vinton Heuck

Director

Sol Choi