Samantha `Sam' Newly

Christina Applegate

Andrea Belladonna

Jennifer Esposito

Howard

Kevin Dunn

Dena

Melissa McCarthy

Frank

Tim Russ

Regina Newly

Jean Smart

Todd

Barry Watson

Bill Jacobs

James Patrick Stuart

Paula Drake

Cybill Shepherd

Wes Green

Dondré Whitfield

Chase Chapman

Rick Hoffman

Instructor

Cooper Thornton

Brad

Teddy Sears

Dr. Andy Adams

Tony Hale

Tommy Wylder

John Taylor

Natalie

Mary-Kate Olsen

Seth

Stephen Rannazzisi

Gigi

Angie Harmon

Amy

Christine Ebersole

Winston Funk

Billy Zane

Kayla Kaminski

Sarah Rafferty

Loretta

Florence Henderson

Tony Dane

McKinley Freeman

Street Musician

Greg Cipes

Brent

Ryan Carnes

Mike

Marsh Mokhtari

Carol

Rachel Cannon

Lindsey

Rebecca Wisocky

Owen

James Tupper

Jason

Brent Tarnol

Willow

Eliza Coupe

Mateo Romero

Mark Ballas

Wife

Robin Gwynne

Tyler Banks

Adam DeVine

Photographer

Indira G. Wilson

Older Woman

Phoebe Dorin

Cheryl Hainstock

Nora Dunn

Gentleman

Charles C. Stevenson

Detective Harp

Stefan Marks

Funeral Director

Barry Finkel

Fanny

Terryn Westbrook

Jerri

Dana Sorman

Guest Star

Wendy Allyn

Allison

Roxana Ortega

Window washer

Rafael Suarez

Cameron

Joni Kempner

Mac Fresh

Andre Ware

Woman

Susie Geiser

Foreman

Steve Wilson

Waitress

Mary Alyce Kania

Guy

Ty Barnett

Guy 2

Troy Dudley

Doctor

Hahn Cho

Cute Guy

Brian D. Phelan

Rafael Grace

Anthony Anderson

Gentleman

Michael A. Templeton

Policeman

Karlton Johnson

African Methodist Minister

Abdoulaye N'Gom

Waitress

Annette M. Lesure

Waitress

Carla Greene

Announcer

Gregory Franklin

Guy 1

Dimitri Lekkos

Crying Kid

Tate Berney

Jackie Johnson

Jackie Johnson

Barista

David Douglas

Mother

Laurie Okin

Roth

Michael Crider

Dolly

Shulie Cowen

Homeless Woman

Denise Gossett

Duncan Weber

Larry Reitzer

Valet Parker

Bryan Keith

13 Year Old Samantha

Amanda Collier

Mickey

Bree Condon

Little Boy

Sayeed Shahidi

Bar patron

Alexandra LeMosle

Fake Dad

Greg Callahan

Waitress

Tara Ochs

Teacher

Terrance Christopher Jones

13 Year Old Dena

Miranda May

Reporter

Ken Rudulph

Baggage Service Rep

David Trice

Philippe

Jean-Pierre Gillain

Pedestrian

Monyque Thompson Scott

Ticket Agent

Anna Zielinski

Roger

Lionel D. Carson

Security Guard

Andre M. Johnson

TSA Agent

Senta Burke

Announcer

Gregory Franklin

Room Service

Justin Warren Downing

TSA Agent

Steven James Price

Director

Jason Winer

Director

Lee Shallat Chemel

Director

Paul Lazarus

Director

Beth McCarthy Miller

Director

Bob Berlinger

Director

Peter Lauer

Director

Joanna Kerns