Dr. Andrew Brown
Treat Williams
Delia Brown
Vivien Cardone
Ephram Brown
Gregory Smith
Amy Abbott
Emily VanCamp
Irv Harper
John Beasley
Edna Abbott
Debra Mooney
Bright Abbott
Chris Pratt
Dr. Harold Abbott
Tom Amandes
Nina Feeney
Stephanie Niznik
Rose Abbott
Merrilyn Gann
Brenda Baxworth
Lee Garlington
Dr. Jake Hartman
Scott Wolf
Madison Kellner
Sarah Lancaster
Hannah Rogers
Sarah Drew
Guest Star
Carter Jenkins
Louise
Jan Broberg
Amanda Hayes
Anne Heche
Guest Star
Elizabeth Mitchell
Guest Star
Jessica Collins
Guest Star
Tom Parker
Guest Star
Shane Haboucha
Guest Star
James Earl Jones
Topher Cole
Lukas Behnken
Colin Hart
Mike Erwin
Guest Star
Jason Beghe
Guest Star
Chris Penn
Guest Star
Jimmy Bennett
Brittany Clark
Whitney Lee
Mindy Wheeler
Erinn Hayes
Reid Bardem
Justin Baldoni
Mr. Jensen
Gordon Johnson
Sharon Hart
Nancy Everhard
Brittany Clark
Whitney Lee
Sam Feeney / Sam Feeney (voice)
Ben Hammond
Ms. Sawaya
Liliana Arredondo
Laynie Hart
Nora Zehetner
Sam Feeney
Ben Hammond
Page
Katie Millar
Martha Thompson
Micaela Nelligan
Mr. Jensen
Gordon Johnson
James Hart
Michael Flynn
Sam Feeney
Ryan Armstrong
Kyle Hunter
Steven R. McQueen
Arnie
Brooks Bedore
Susie Clark
Haley McCormick
Kayla
Valerie Welcker
Dr. Chao
Freda Foh Shen
Jay
Charlie Weber
Julia Brown
Brenda Strong
Student
Jonathan Rudy
Principal Ackerman
David Downs
Coach Austin / The Do-Gooder
Scott Christopher
Delia's Friend
Lorna Gabrielle Balfour