Pete

Mark Duplass

Kevin

Steve Rannazzisi

Ruxin

Nick Kroll

Andre

Paul Scheer

Taco

Jon Lajoie

Jenny

Katie Aselton

Grandpa Duke

Robert Wagner

Sushi Chef

Timothy Olyphant

Dirty Randy / Dirty Randy (voice)

Seth Rogen

Guest Star

Rich Eisen

Himself

Jim McMahon

Sofia

Nadine Velazquez

DeRon

J.B. Smoove

Kristin Cavallari

Kristin Cavallari

Rupert Ruxin

Jeff Goldblum

Himself

Adrian Peterson

Gumma Eve

Lee Meriwether

Ben

Ryan Hansen

Frank 'The Body' Gibiatti / Frank Gibiatti

Ike Barinholtz

Lane

Zach Woods

Ellie

Alina Foley

Himself

Deion Sanders

Guest Star

Robert Griffin III

Himself

Ryan Fitzpatrick

Lindsay

Lindsay Sloane

Martha

Julia Duffy

Judge Hobart

Phil Reeves

Wanda

Eve Brenner

Piano Store Guy

Steve Agee

Shiva

Janina Gavankar

Dr. Levenson

Ben Lawson

Rafi

Jason Mantzoukas

Gina Gibiatti

Brooklyn Decker

Japanese Sushi Chef

Kenji Nakamura

Donny 'The Seed' Sedowsky

Ken Marino

Himself

Trent Richardson

Guest Star

Matt Kalil

Dr. Melvoy's Daughter

Heather Hegeman

Dr. Pete Wyland

John Ross Bowie

Taco's Abandoned Patient

Michael Naughton

Gail

Andrea Savage

Morgue Worker

David Dastmalchian

Paintball Employee

Frederick Lawrence

Dr. Ewing

Andrew Secunda

Sutton

Melissa Ordway

Himself

DeSean Jackson

Tug

Charlie Sanders

Michelle

Ingrid Haas

Himself

Jason Witten

Mr. Rosenthal

Rick Overton

Miles Miller

Bob Odenkirk

Old Lady 1

Bonnie Hellman

Taco's Lady Patient

Jacquie Barnbrook

Abby

Elizabeth Hendrickson

Cute Girl in Bar

Milana Vayntrub

George

Amanda Lund

Colonoscopy Nurse

Nicol Paone

Charlie McCrudden

Connor Kalopsis

Guest Star

Ryan Kalil

Rafi's Landlord

Pedro Lopez

Old Lady 2

Brenda Ballard

Russell / Dr. Deramo

Rob Huebel

Class Instructor

Roxana Ortega

Santa Claus

Richard Riehle

Tiffany

Sabina Gadecki

Guest Star

Jerry Jones

Taco's Kid Patient

Tristian Chase

Meegan

Leslie Bibb

Pam

Christen Sussin

Valet

Marshall Manesh

Trixie Von Stein

Jayma Mays

Shoe Store Clerk

Hunter Cope

Elderly Woman

Maree Cheatham

Lauren

Meredith Giangrande

Kayden

Kayden Kross

Guest Star

Felix Jones

Bill Haddock / Bill

Seth Morris

Guest Star

Jeremiah Ratliff

Baby Geoffrey

Adam Karchmer

Bethesda

Rob Riggle

Chalupa Batman

Jason David

Ted

Adam Brody