Host

Derek Waters

Narrator

Tiffany Haddish

Deborah Sampson

Evan Rachel Wood

Guest Star

Seth Rogen

Gordon Cooper / Fred Rogers / Ernest Thompson Seton

Colin Hanks

Stetson Kennedy / Elisha Gray / Robert Wilson

Jason Ritter

Guest Star

Vanessa Hudgens

Guest Star

Tatiana Maslany

Guest Star

Randall Park

Guest Star

Questlove

Guest Star

Abbi Jacobson

Vincenzo Peruggia / Elvis Presley / William Mulholland

Jack Black

Guest Star

Mae Whitman

Guest Star

Kirsten Dunst

Narrator

Paget Brewster

Narrator

Amber Ruffin

Guest Star

Justin Long

Guest Star

Method Man

Rose Valland

Busy Philipps

Ponce De Leon / Marshall Ratliff / Johnny Cash

Johnny Knoxville

Guest Star

Kat Dennings

Guest Star

David Harbour

Guest Star

Vanessa Bayer

Guest Star

Allison Tolman

Guest Star

Josh Charles

Guest Star

Claudia O'Doherty

Guest Star

Lyric Lewis

Various

Bennie Arthur

Clara Barton

Mandy Moore

Guest Star

Raven-Symoné

Guest Star

Donald Faison

Edward Cope / Meriwether Lewis / James Monroe

Tony Hale

Guest Star

Jorma Taccone

Guest Star

Paul Scheer

Guest Star

Jimmy O. Yang

Guest Star

Amber Tamblyn

Guest Star

Ali Stroker

Various

Maria Blasucci

Guest Star

Kimiko Glenn

Guest Star

"Weird Al" Yankovic

Guest Star

Martin Starr

Various

Craig Cackowski

Guest Star

Joel McHale

Guest Star

Jane Krakowski

Guest Star

Samm Levine

Guest Star

Jillian Bell

Various

Jeremy J. Tutson

Various

Tymberlee Hill

Various

Sarah Burns

James Dunn

Alexander Skarsgård

— / H.R. Haldeman / General Andrew Jackson

Jack McBrayer

Various

Michael Daniel Cassady

Various

Adam Nee

King Charles II / Thomas Edison / Jim Bowie

Chris Parnell

D.B. Cooper / Frédéric Auguste Bartholdi / William Clark

Taran Killam

Scientist / Rough Rider / Bootlegger

Kyle David Crosby

Various / Fireman

Michael Coleman

Himself - Narrator / Museum Guard

Eric Edelstein

Director

Derek Waters

Director

Jeremy Konner