William Masters

Michael Sheen

Virginia Johnson

Lizzy Caplan

Dr. Barton Scully

Beau Bridges

Libby Masters

Caitlin FitzGerald

Betty DiMello

Annaleigh Ashford

Guest Star

Judy Greer

Dr. Austin Langham

Teddy Sears

Guest Star

Justin Andrews

Guest Star

Melissa Rey

Lester Linden

Kevin Christy

Guest Star

Alysia Reiner

Guest Star

Aaron Abrams

Guest Star

Joel Brooks

Guest Star

Mary Birdsong

Guest Star

Rafael Feldman

Guest Star

Michael Scott Allen

Guest Star

Nick Clifford

Guest Star

Lisa Banes

Daniel Logan

Josh Charles

Guest Star

John Gleeson Connolly

Guest Star

John Billingsley

Guest Star

Joanna Canton

Guest Star

Steve Bannos

Guest Star

Yan Feldman

Guest Star

Nicole Cummins

Guest Star

Melissa Center

Guest Star

Frances Fisher

Guest Star

Rich Sommer

Dr. Nancy Leveau

Betty Gilpin

Tessa Johnson

Isabelle Fuhrman

Jane Martin

Heléne Yorke

Guest Star

Rachelle Dimaria

Guest Star

Camryn Manheim

Guest Star

Chloe Dworkin

Guest Star

Jack Impellizzeri

Guest Star

Erin Karpluk

Dr. Ethan Haas

Nicholas D'Agosto

Harry Eshelman

Michael O'Keefe

Guest Star

Enuka Okuma

Guest Star

Amber Petty

Dr. Lillian DePaul

Julianne Nicholson

Guest Star

Danny Jacobs

Guest Star

James Liebman

Guest Star

Bryce Johnson

Guest Star

Brian Unger

Guest Star

Jacqueline Hahn

Guest Star

Donald Sage Mackay

Guest Star

Rick Peters

Guest Star

Jaeden Lieberher

Guest Star

Amanda Quaid

Tessa Johnson

Kayla Madison

Louise Bell

Niecy Nash

Herb Spleeb

Jack Laufer

Guest Star

Lily Rains

Guest Star

Stephen Root

Guest Star

Jake Lockett

Jenny Masters

Alyvia Alyn Lind

Guest Star

Mildred Marie Langford

Guest Star

Paul Cassell

Guest Star

Romy Rosemont

Guest Star

Alex Weed

Guest Star

Frederick Keeve

Guest Star

Michael McColl

Dr. Art Dreesen

Jeremy Strong

Guest Star

Rondi Reed

Guest Star

Caiden Milick

Guest Star

Chelsea Maidhof

Guest Star

Armand Vasquez

Guest Star

Charles Shaughnessy

Guest Star

Peter Holden

Guest Star

Corey Reynolds

Guest Star

Kelli O'Hara

Guest Star

Julia McIlvaine

Guest Star

Nathan Mohebbi

Henry Johnson

Cole Sand

Margaret Scully

Allison Janney

Paul Edley

Benjamin Koldyke

Vivian Scully

Rose McIver

Estabrooks Masters

Ann Dowd

Barbara Sanderson

Betsy Brandt

Flo Packer

Artemis Pebdani

Robert Franklin

Jocko Sims

Helen Schiff

Sarah Silverman

Bram Keller

David Walton

Gene Moretti

Greg Grunberg

George Johnson

Mather Zickel

Chancellor Fitzhugh

Garrett M. Brown

Ronald Sturgis

Colin Woodell