Dr. Beaumont Rosewood Jr.

Morris Chestnut

Tara Milly Izikoff (aka TMI)

Anna Konkle

Detective Annalise Villa

Jaina Lee Ortiz

Donna Rosewood

Lorraine Toussaint

Captain Ira Hornstock

Domenick Lombardozzi

Pippy Rosewood

Gabrielle Dennis

Guest Star

Sherri Shepherd

Guest Star

Joy Bryant

Guest Star

Chris Bosh

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Vondie Curtis-Hall

Captain Ryan Slade

Eddie Cibrian

Guest Star

Adrian Pasdar

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Taye Diggs

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Scott Porter

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Nicole Ari Parker

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Salli Richardson-Whitfield

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Mackenzie Astin

Guest Star

Emayatzy Corinealdi

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Cole Bernstein

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Rasheeda Frost

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Sam Huntington

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Kamal Angelo Bolden

Guest Star

Kurt Fuller

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Matthew Glave

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Steve Whatley

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Antwon Tanner

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Michael Irby

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Alysia Reiner

Guest Star

Lauren Bowles

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H. Richard Greene

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Stephen Full

Guest Star

Rodney To

Guest Star

Nikea Gamby-Turner

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Amanda Leighton

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Henry Czerny

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John Gabriel

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Jimmy Ramirez

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Shi Ne Jong Nielson

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Cara Pifko

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Phil Abrams

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Rey Gallegos

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Merle Dandridge

Guest Star

Shannon Lucio

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Christopher J. Johnson

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Antonio Jaramillo

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Michelle Bonilla

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Stacy Hall

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Juan Pablo Di Pace

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Mark Atteberry

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Tia Mowry-Hardrict

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Matthew Risch

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Lisa Vidal

Guest Star

Samuel Huntington

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Chad Lindberg

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Eric Nenninger

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Asante Jones

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David Julian Hirsh

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Danielle Rayne

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Kavita Patil

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Adam Kulbersh

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Katherine Boecher

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Stella Farentino

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Thomas Silcott

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Andrew Thacher

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Michael Hogan

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Christina Moses

Guest Star

Chance Harlem Jr.

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Deborah Rayne

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Rickey Eugene Brown

Guest Star

Kassandra Kanaar

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Marco Sanchez

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Christopher Carroll

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Rick Gonzalez

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Tom Beyer

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Matt Cedeno

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William Charlton

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Sarah Domin

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Laura Julian

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Mark Rolston

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Jonathan Craig Williams

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Rayna Tharani

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Torrance Jordan

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Christopher B. Duncan

Guest Star

Quincy Ndekwe

Guest Star

Lisa Banes

Guest Star

Shaan Sharma

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Ryan W. Garcia

Guest Star

Brian Balzerini

Guest Star

Sheryl Lee

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John Billingsley

Guest Star

Sprague Grayden

Guest Star

Mel Fair

Guest Star

Keisuke Hoashi

Guest Star

Mark Knudsen

Guest Star

Michael Trotter

Guest Star

Nahesi Crawford

Guest Star

Samantha Gros

Guest Star

Abhi Trivedi

Guest Star

Allius Barnes

Guest Star

Kim H. Howard