Jackie Peyton

Edie Falco

Zoey Barkow

Merritt Wever

Dr. O'Hara

Eve Best

Mohammed 'Mo-Mo' de la Cruz

Haaz Sleiman

Dr. Fitch Cooper

Peter Facinelli

Eddie Walzer

Paul Schulze

Kevin Peyton

Dominic Fumusa

Thor Lundgren

Stephen Wallem

Dr. Akalitus

Anna Deavere Smith

Grace Peyton

Ruby Jerins

Fiona Peyton

Daisy Tahan

Bernard Zimberg

Eli Wallach

Fiona Peyton

Mackenzie Aladjem

Mrs. Zimberg

Lynn Cohen

Ginny Flynn

Elizabeth Marvel

Irate Man

T. Ryder Smith

Beth

April Lee Hernandez

Eileen

Ching Valdes-Aran

Amy Greenfield

Alexie Gilmore

Mrs. Vogal

Kristen Connolly

Sam

Arjun Gupta

Kelly Oliver

Bronwen Booth

Maureen Cooper

Blythe Danner

Neil Nutterman

Victor Garber

Zak

Zak Orth

Stephanie

Tomorrow Baldwin Montgomery

Kaitlyn Flynn

Cassady Leonard

Bonnie

Anna Koonin

God / Donald

Michael Buscemi

Skip Nannerine

Christopher Evan Welch

Melissa Greenfield

Jill Flint

Tap Instructor

Eddie Korbich

Mrs. Greenfield

Andrea Martin

Mother

Erin Dilly

Dr. Carrie Roman

Betty Gilpin

Model

Nicole LaLiberte

Mother

Angela Pietropinto

Mrs. Dzubenko

Adinah Alexander

Mrs. Scheinhorn

Swoosie Kurtz

Guest Star

Lazaro Perez

School Nurse / Connie

Starla Benford

Terry

Jay Wilkison

Policeman Brother

Quincy Dunn-Baker

Lenny

Lenny Jacobson

Dzubenko Son

Dennis Staroselsky

Lisa

Caitlin Gold

Paula

Judith Ivey

Mr. Batali

Daniel London

Lenny

Lenny Jacobsen

Lori

Yetta Gottesman

Nurse

Haley Zale

Guest Star

Joe Lisi

Intestine Man

Chuck Cooper

Pedophile

James Georgiades

Lucille Marinovich

Janie Kelly

Fireman Brother

Michael Giese

Andy Singer

Christopher Abbott

Dzubenko Daughter

Saskia Slaaf

Peter

Justin Grace

Paramedic

William Watkins

Paramedic

Joseph Ackler

Hospital Transporter

Harry L. Seddon

Frank Verelli

Adam Ferrara

Paramedic

Katie Flahive

Dr. Ike Prentiss

Morris Chestnut

EMT

Steven Lee Merkel

Dr. Mike Cruz

Bobby Cannavale

Paramedic

R.A. Guirand

EMT

Amina Robinson

Antoinette

Julie White

Kelly Slater

Gbenga Akinnagbe

Gabe

Michael Esper

Dr. Bernard Prince

Tony Shalhoub

Charlie Cruz

Jake Cannavale

Bill / Seizure Man

Bill Sage

Mia

Laura Benanti

Marta

Marcy Harriell

Johanes Karlsen

Jeremy Shamos

Officer Ryan

René Ifrah

EMT

Mark McDonald

EMT Hannah

Chinasa Ogbuagu

Paramedic

Jamila Webb

Barry Wolfe

Mark Feuerstein