Jackie Peyton

Edie Falco

Zoey Barkow

Merritt Wever

Dr. O'Hara

Eve Best

Dr. Cooper

Peter Facinelli

Thor Lundgren

Stephen Wallem

Eddie Walzer

Paul Schulze

Kevin Peyton

Dominic Fumusa

Mo-Mo

Haaz Sleiman

Mrs. Gloria Akalitus

Anna Deavere Smith

Grace Peyton

Ruby Jerins

Ginny Flynn

Elizabeth Marvel

Fiona Peyton

Mackenzie Aladjem

Martin Vobernick

Patrick Breen

John Decker

Harvey Fierstein

Georgia

Jennifer Ferrin

City Island Clerk

Xosha Roquemore

Sam

Arjun Gupta

Bill / Seizure Man

Bill Sage

Renata Thurber

Marion Ross

Line Guy 1

Greg Siff

God / Donald

Michael Buscemi

Mrs. Feinberg

Sondra James

Sarah Khouri

Julia Ormond

Brooke

Deidre Goodwin

Marco Prince

Jimmy Gary Jr.

Dr. Carrie Roman

Betty Gilpin

Line Guy 2

Jeremy Zorek

Lily

Justine Cotsonas

Young Mother

Margaret Anne Florence

Lexie

Allison Case

Wimpy Man

Raymond McAnally

Keith Fogulson

Rich Topol

Methadone Addict

Jeffrey Ware

Tim

Jefferson Mays

Steve

Pedro Pascal

Lenny

Lenny Jacobson

Whitney Prince

Rosalyn Coleman

Libby Sussman

Barbara Barrie

Nurse

Haley Zale

Dina

Susan Mosher

Mr. Spagnolo

Paul Feig

CF Lab Tech

Jolly Abraham

George

Ashley Springer

Suzy

Susan Pourfar

Kaitlyn Flynn

Cassady Leonard

Dr. Lindsey

Seth Gilliam

Trey

Chris Jackson

Miguel

Frank Pando

Hospital Transporter

Harry L. Seddon

Frank Verelli

Adam Ferrara

Paramedic

Katie Flahive

Dr. Ike Prentiss

Morris Chestnut

EMT

Steven Lee Merkel

Dr. Mike Cruz

Bobby Cannavale

Fiona Peyton

Daisy Tahan

Paramedic

R.A. Guirand

EMT

Amina Robinson

Antoinette

Julie White

Kelly Slater

Gbenga Akinnagbe

Gabe

Michael Esper

Dr. Bernard Prince

Tony Shalhoub

Charlie Cruz

Jake Cannavale

Mia

Laura Benanti

Paramedic

Joseph Ackler

Marta

Marcy Harriell

Johanes Karlsen

Jeremy Shamos

Paramedic

William Oliver Watkins

Officer Ryan

René Ifrah

EMT

Mark McDonald

EMT Hannah

Chinasa Ogbuagu

Paramedic

Jamila Webb

Barry Wolfe

Mark Feuerstein