Peter Griffin / Brian Griffin / Stewie Griffin / Glenn Quagmire / Tom Tucker / Dr. Elmer Hartman
Seth MacFarlane
Lois Griffin / Tricia Takanawa / Loretta Brown
Alex Borstein
Lois Griffin
Alex Borstein
Chris Griffin
Seth Green
Meg Griffin
Mila Kunis
Cleveland Brown (voice) / Bruce the Performance Artist (voice) / Cleveland Brown
Mike Henry
Jillian Russell (voice) / Mrs. Lockhart (voice)
Drew Barrymore
Adam West (voice) / Mayor Adam West / Ace Merrill (voice)
Adam West
Diane Simmons / Girl (voice) / Charles Lindbergh's Wife (voice)
Lori Alan
Brandee
Jessica Barth
The Cow
Ricardo Montalban
Joe Swanson (voice) / Joe Swanson / Joey Duchamp
Patrick Warburton
Tracy
Harvey Fierstein
James Woods (voice) / James Woods as General Veers (voice) / Family Guy James Woods
James Woods
Andy Garcia's Date
Alex Breckenridge
Angela (voice) / Angela as Mon Mothma (voice)
Carrie Fisher
Himself
Barry Manilow
Bert (voice) / Bert / Judge (voice)
Bryan Cranston
Boyfriend
Chace Crawford
Audience Member / Target Employee (voice) / Milo (voice)
Steve Callaghan
Thelma
Phyllis Diller
Jerome (voice) / (voice) / Cleveland Brown Jr. (voice)
Kevin Michael Richardson
Carl (voice) / Bob Belcher (voice) / Carl as Yoda (voice)
H. Jon Benjamin
Anna
Amanda Bynes
Himself
Simon Cowell
Lisa / Donna
Camille Guaty
Additional Voices
Bruce Lanoil
(voice) / Hammer (voice) / Guy in Line (voice)
Damien Fahey
The Doctor (archive footage)
Tom Baker
David Letterman (as Evil Dave)
Dave Van Dam
Meaty the Quick-to-Anger Clown
Mark Hentemann
Another Death (voice) / Announcer (voice) / TV Announcer (voice)
John Viener
Bonnie Swanson (voice)
Jennifer Tilly
(voice) / Various (voice) / Olivia (voice)
Rachael MacFarlane
Herself
Paula Abdul
Connie D'Amico (voice) / Beth / Teenage Girl (voice)
Lisa Wilhoit
Himself
Jamie Farr
Lisa Simpson
Audrey Wasilewski
Himself
Randy Jackson
Kid (voice) / (voice) / Kid in Audience (voice)
Max Burkholder
Mort Goldman
Johnny Brennan
Additional Voices
Tamera Mowry
Judge (voice) / (voice) / Ollie Williams (voice)
Phil LaMarr
Principal Shepherd (voice) / Mike Brady (voice) / Reporter (voice)
Gary Cole
(voice) / Ernie the Giant Chicken (voice) / Man (voice)
Danny Smith
Himself (archive footage)
Conway Twitty
(voice) / Man at DMV (voice) / Cat (voice)
Chris Sheridan
Gerardo / Various Mexican Guys
Alex Fernandez
Clark Griswold
Chevy Chase
Ellen Griswold
Beverly D'Angelo
Baby Susie Swanson (Inner Voice) (voice) / Captain Jean-Luc Picard (voice) / Narrator (voice)
Patrick Stewart
Additional Voices
Erin Hayes
Fred Flintstone (voice) / (voice) / Fred Flintstone
Jeff Bergman
Elizabeth Shue / Blonde
Christa Campbell
Mexican 5
Gabriel Iglesias
Additional Voices
James Burkholder
Richard Gere (voice) / Hand #1 (voice) / Rupert (voice)
David Boat
Jackée Harry / Bernice
Wendy Raquel Robinson
Additional Voices
Pat Crawford Brown
(voice) / George W. Bush (voice) / Various (voice)
Kirker Butler
(voice) / Various (voice) / Police Officer (voice)
Ralph Garman
Himself (as Simply Red)
Mick Hucknall
David Anthony Pizzuto
(voice) / Man (voice) / Jesus Christ (voice)
Alec Sulkin
Additional Voices
Carla Delaney
Additional Voices
Denis Martell
Additional Voices
Barclay DeVeau
Additional Voices
Stephen Stanton
(voice) / Muriel Goldman (voice) / Girl in a Scavenger Hunt
Nicole Sullivan
Rush Limbaugh / Red 6
Rush Limbaugh
(voice) / Teenage Girl (voice) / Vegas Waitress (voice)
Mae Whitman
Anthony Tavera
Additional Voices
Ted McGinley
Cleveland Brown (voice)
Arif Zahir
Additional Voices
Anthony Tavera
Dr. Rumack (archive footage)
Leslie Nielsen
Additional Voices
Brendyn Bell
Don Thai Theerathada
Herself
Helen Reddy
Additional Voices
D.D. Howard
Additional Voices
Mark DeCarlo
Additional Voices
Sebastian Siegel
Connor Trinneer
Willem Dafoe
David Anthony Pizzuto
Thai Pilot
Don Theerathada
Mort Goldman (voice) / Horace (voice) / Man #2 (voice)
John G. Brennan
Dave Wittenberg
Additional Voices
Jack Samson
Brian Blessed
Man (voice) / Various (voice) / Peter's Customer
Chris Cox
Additional Voices
Anthony Skillman
John Bender
Judd Nelson
(voice) / Meg Griffin (singing voice) / Amy Grant (voice)
Tara Strong
Man (voice) / Ornithologist (voice) / Dr. Bruce Kaplan (voice)
Wally Wingert
Erinn Hayes
(voice) / John Madden (voice) / Undecided Voter (voice)
Fred Tatasciore
(voice) / Squirrel (voice) / Parrot (voice)
Dee Bradley Baker
Jeff Witzke
Johnny Knoxville
(voice) / Morgan Freeman (voice) / Patrick Swayze
Josh Robert Thompson
Joyce Kinney (voice) / (voice) / Joyce Kinney
Christine Lakin
Ruth (voice) / (voice) / Little Miss Muffet (voice)
Emily Osment
(voice) / Student (voice) / Eighth Grader (voice)
Lucas Grabeel
Donna Tubbs (voice) / Claire Huxtable (voice) / Muhammad Ali's Wife (voice)
Sanaa Lathan
Doug (voice) / Priest (voice) / Card Store Owner (voice)
Chris Parnell
(voice) / Meg Griffin (voice)
Lacey Chabert
Wild Wild West (voice) / Mayor Wild West (voice) / Sam Elliott (voice)
Sam Elliott
Mr. Weed (voice) / Jonathan Weed (voice) / (voice)
Carlos Alazraqui
(voice) / Lifeguard / Dutch Dog (voice)
Travis Bowe
(voice) / Little Boy (voice) / Boy (voice)
Jonathan Morgan Heit
Patty (voice) / Additional Voices (voice) / (voice)
Martha MacIsaac
(voice) / Mother (voice) / Rita (voice)
Nana Visitor
Kid (voice) / (voice) / Cobain (voice)
Issac Ryan Brown
(voice) / Chinese Peasant (voice) / Giant Crab (voice)
Mike Desilets
Kevin Swanson (voice) / Michael Pulaski (voice) / Michael Bublé (voice)
Scott Grimes
Kanye Canes (voice) / Brick Baker (voice) / Stephen A. Smith (voice)
Jay Pharoah
Death (voice) / Death / Super Death (voice)
Adam Carolla
(voice) / Various (voice) / Jolly Farm Executive #3 (voice)
Gary Janetti
(voice) / Kid (voice) / Randall (voice)
Colin Ford
(voice) / Kelsey Grammer (voice) / Lion (voice)
Jon Daly
(voice) / Smurf #2 (voice) / Buff Guy (voice)
Mike Barker
Various (voice) / Charles Montrose / Vet (voice)
Butch Hartman
(voice) / Various (voice) / Hope Shanowski (voice)
Stacey Scowley
(voice) / Dentist (voice) / John Travolta (voice)
Jerry Lambert
Hope (voice) / Bozo's Client / Sylvester Stallone's Assistant (voice)
Judy Greer
(voice) / Employee #1 (voice) / Peter's Customer
Patrick Meighan
Girl (voice) / Opie's Daughter (voice) / Bowling Alley Girl (voice)
Ava Acres
Esther (voice)
Christina Milian
(voice) / Baby on Big Wheel (voice) / James Taylor (voice)
Artie Johann
(voice) / Peter's Customer / Tea Party Member (voice)
Julius Sharpe
(voice) / Jewish Man (voice) / Dick Clark (voice)
Joey Slotnick
(voice) / Todd (voice) / Bobby Briggs (voice)
Will Sasso
Watson (voice) / Mr. Henderson (voice) / Cyrano de Bergerac (voice)
Cary Elwes
Adult Fan (voice) / Roberto (voice) / Nurse (voice)
Ignacio Serricchio
Charles Yamamoto (voice) / Octopus (voice) / Korean General (voice)
Robert Wu
(voice) / Prowler (voice) / Focus Group Tester (voice)
Chris Regan
Preston Lloyd (voice)
Peter Macon
Francis Griffin (voice)
Charles Durning
Mrs. Kraner / Sandy Belford (voice) / Janet
Debra Wilson
(voice) / Jason Voorhees (voice) / Vacuum Repairman (voice)
Jackson Douglas
(voice) / Courtney / Sandra (voice)
Heléne Yorke
Garth Brooks (voice) / George H. W. Bush / Johnny Depp (voice)
Ross Marquand
Chinese Woman (voice) / Yoko Oyes (voice) / Waitress (voice)
Charlet Chung
Stella (voice)
Marlee Matlin
Ruth Cochamer (voice)
Natasha Melnick
(voice)
Wellesley Wild
Henessy (voice) / Big Fat Paulie (voice) / Bronx Guy #1 (voice)
Michael Chiklis
Ms. Hobson / Kim Cattrall (voice) / Daycare Teacher
Mo Collins
Isaac (voice) / Australian Man (voice) / Wombat (voice)
Liam McIntyre
Pinocchio (voice) / Leonardo DiCaprio (voice) / Various (voice)
Hunter Gomez
Vinny (voice) / Tony Sirico
Tony Sirico
Kid (voice) / Preschooler (voice) / Water Park Kid (voice)
Max Charles
(voice) / Wheel-Cher (voice)
Catherine Reitman
Abusive Father (voice) / Customer (voice) / Gym Instructor (voice)
Khary Payton
Cellmate (voice) / Drug Dealer (voice) / Tony Montana (voice)
Rolando Molina
(voice) / Dean Martin (voice) / Millipede (voice)
Chris Diamantopoulos