Peter Griffin/Stewie Griffin/Brian, the dog/Tom Tucker/Glenn Quagmire
Seth MacFarlane
Lois Griffin
Alex Borstein
Lois Griffin / Tricia Takanawa / Loretta Brown
Alex Borstein
Chris Griffin
Seth Green
Meg Griffin
Mila Kunis
Cleveland Brown (voice) / Bruce the Performance Artist (voice) / Cleveland Brown
Mike Henry
Himself
Rich Appel
Pam Fishman
Elizabeth Banks
Himself
Brian Williams
Reginald Barrington
Hank Azaria
Joe Swanson (voice) / Joe Swanson / Joey Duchamp
Patrick Warburton
Herself
Anne Murray
Himself
Alan Bennett
Randy
Giovanni Ribisi
Adam West (voice) / Mayor Adam West / Ace Merrill (voice)
Adam West
Esther (voice)
Christina Milian
Edward Scissorhands
Johnny Depp
Himself
Bob Costas
Buxom Woman / Hispanic Woman
Sofía Vergara
Himself
Tim Gunn
Overweight Guy
Ryan Reynolds
Portrait Griffin
Sean Bean
Francine Smith
Wendy Schaal
Principal Shepherd (voice) / Mike Brady (voice) / Reporter (voice)
Gary Cole
Herself
Carly Simon
Herself
Padma Lakshmi
Man (voice) / Various (voice) / Peter's Customer
Chris Cox
Statue Griffin
Tom Hiddleston
Homer Simpson
Dan Castellaneta
Bonnie Swanson (voice)
Jennifer Tilly
Mahmoud
Omid Abtahi
Pewterschmidt Industries Executive
John de Lancie
(voice) / Student (voice) / Eighth Grader (voice)
Lucas Grabeel
Toby
Keir Gilchrist
Jerome (voice) / (voice) / Cleveland Brown Jr. (voice)
Kevin Michael Richardson
Old Woman / Teacher
Megan Hilty
(voice) / Meg Griffin (voice)
Lacey Chabert
Herself
Christine Baranski
Hank Hill
Mike Judge
Joyce Kinney (voice) / (voice) / Joyce Kinney
Christine Lakin
(voice) / Chinese Peasant (voice) / Giant Crab (voice)
Mike Desilets
Mort
Johnny Brennan*
Jillian Russell (voice) / Mrs. Lockhart (voice)
Drew Barrymore
Himself
Bill Maher
Himself
J.J. Abrams
Another Death (voice) / Announcer (voice) / TV Announcer (voice)
John Viener
Himself
Ron Jones
Carl (voice) / Bob Belcher (voice) / Carl as Yoda (voice)
H. Jon Benjamin
(voice) / Teenage Girl (voice) / Vegas Waitress (voice)
Mae Whitman
Herself
Sandra Bernhard
Ruth (voice) / (voice) / Little Miss Muffet (voice)
Emily Osment
Mike Damone
Robert Romanus
Amanda Barrington
Emma Roberts
Mort Goldman / Horace
Johnny Brennan
(voice) / Various (voice) / Olivia (voice)
Rachael MacFarlane
Kid (voice) / Preschooler (voice) / Water Park Kid (voice)
Max Charles
Himself
Robert Loggia
Himself
Walter Murphy
Brooke
Jessica Biel
Aunt Helen
Ellen Albertini Dow
Customer
Andrew Hibbard
Ben Fishman
Martin Spanjers
Himself
Jon Hamm
Himself
Nick Cannon
Audience Member / Target Employee (voice) / Milo (voice)
Steve Callaghan
Pinocchio (voice) / Leonardo DiCaprio (voice) / Various (voice)
Hunter Gomez
Additional Voices
Alex Breckenridge
Fred Flintstone (voice) / (voice) / Fred Flintstone
Jeff Bergman
Herself
Sharon Osbourne
(voice) / Various (voice) / Police Officer (voice)
Ralph Garman
Carolyn
Kat Foster
Additional Voices
Stephanie Escajeda
Additional Voices
Brad Goreski
Himself
Dick Wolf
Patty (voice) / Additional Voices (voice) / (voice)
Martha MacIsaac
Additional Voices
Joe Lomonaco
Additional Voices
Ted Jessup
(voice) / Various (voice) / Jolly Farm Executive #3 (voice)
Gary Janetti
Himself
Mark Burnett
(voice) / Opie (voice) / Opie
Mark Hentemann
Additional Voices
James Burkholder
(voice) / Employee #1 (voice) / Peter's Customer
Patrick Meighan
Judge (voice) / (voice) / Ollie Williams (voice)
Phil LaMarr
Carol West
Julie Hagerty
Ruth Cochamer (voice)
Natasha Melnick
Kid (voice) / (voice) / Kid in Audience (voice)
Max Burkholder
(voice) / Little Boy (voice) / Boy (voice)
Jonathan Morgan Heit
Additional Voices
Sara Fletcher
(voice) / Peter's Customer / Tea Party Member (voice)
Julius Sharpe
Kevin Swanson (voice) / Michael Pulaski (voice) / Michael Bublé (voice)
Scott Grimes
(voice) / Muriel Goldman (voice) / Girl in a Scavenger Hunt
Nicole Sullivan
Baby Lois
Tatum Hentemann
(voice) / Ernie the Giant Chicken (voice) / Man (voice)
Danny Smith
Additional Voices
Cleo King
Charles Yamamoto (voice) / Octopus (voice) / Korean General (voice)
Robert Wu
(voice) / Dentist (voice) / John Travolta (voice)
Jerry Lambert
Additional Voices
Rhea Seehorn
Additional Voices
Fiona Gubelmann
(voice) / Kid (voice) / Randall (voice)
Colin Ford
(voice) / Man (voice) / Jesus Christ (voice)
Alec Sulkin
Cindy
Ginger Gonzaga
Diane Simmons / Girl (voice) / Charles Lindbergh's Wife (voice)
Lori Alan
(voice) / Man at DMV (voice) / Cat (voice)
Chris Sheridan
Additional Voices
Sherry Romito
Additional Voices
Bruce McGill
Cleveland Brown (voice)
Arif Zahir
Black Co-Worker
Michael Clarke Duncan
Additional Voices
Jill Talley
(voice) / Wheel-Cher (voice)
Catherine Reitman
Gayjacker (archive footage)
Jim Parsons
Additional Voices
Joshua Rush
(voice) / Morgan Freeman (voice) / Patrick Swayze
Josh Robert Thompson
Additional Voices
Wellesley Wild
Herself
Cheryl Tiegs
Mike Biggs
Billy Gardell
Man (voice) / Ornithologist (voice) / Dr. Bruce Kaplan (voice)
Wally Wingert
(voice) / John Madden (voice) / Undecided Voter (voice)
Fred Tatasciore
(voice) / Todd (voice) / Bobby Briggs (voice)
Will Sasso
(voice) / Mother (voice) / Rita (voice)
Nana Visitor
Baby Susie Swanson (Inner Voice) (voice) / Captain Jean-Luc Picard (voice) / Narrator (voice)
Patrick Stewart
Mort Goldman (voice) / Horace (voice) / Man #2 (voice)
John G. Brennan
Additional Voices
Johann Urb
Denise
Jessica Stroup
Additional Voices
Kadeem Hardison
Additional Voices
David Lodge
(voice) / Squirrel (voice) / Parrot (voice)
Dee Bradley Baker
(voice) / Smurf #2 (voice) / Buff Guy (voice)
Mike Barker
Additional Voices
Jed Rees
Additional Voices
Alexis Knapp
(voice) / Hammer (voice) / Guy in Line (voice)
Damien Fahey
Angela (voice) / Angela as Mon Mothma (voice)
Carrie Fisher
Donna Tubbs (voice) / Claire Huxtable (voice) / Muhammad Ali's Wife (voice)
Sanaa Lathan
Doug (voice) / Priest (voice) / Card Store Owner (voice)
Chris Parnell
(voice) / Meg Griffin (singing voice) / Amy Grant (voice)
Tara Strong
Connie D'Amico (voice) / Beth / Teenage Girl (voice)
Lisa Wilhoit
Wild Wild West (voice) / Mayor Wild West (voice) / Sam Elliott (voice)
Sam Elliott
Mr. Weed (voice) / Jonathan Weed (voice) / (voice)
Carlos Alazraqui
(voice) / Lifeguard / Dutch Dog (voice)
Travis Bowe
Kid (voice) / (voice) / Cobain (voice)
Issac Ryan Brown
Kanye Canes (voice) / Brick Baker (voice) / Stephen A. Smith (voice)
Jay Pharoah
Death (voice) / Death / Super Death (voice)
Adam Carolla
(voice) / George W. Bush (voice) / Various (voice)
Kirker Butler
(voice) / Kelsey Grammer (voice) / Lion (voice)
Jon Daly
Bert (voice) / Bert / Judge (voice)
Bryan Cranston
Various (voice) / Charles Montrose / Vet (voice)
Butch Hartman
James Woods (voice) / James Woods as General Veers (voice) / Family Guy James Woods
James Woods
(voice) / Various (voice) / Hope Shanowski (voice)
Stacey Scowley
Hope (voice) / Bozo's Client / Sylvester Stallone's Assistant (voice)
Judy Greer
Girl (voice) / Opie's Daughter (voice) / Bowling Alley Girl (voice)
Ava Acres
(voice) / Baby on Big Wheel (voice) / James Taylor (voice)
Artie Johann
(voice) / Jewish Man (voice) / Dick Clark (voice)
Joey Slotnick
Watson (voice) / Mr. Henderson (voice) / Cyrano de Bergerac (voice)
Cary Elwes
Adult Fan (voice) / Roberto (voice) / Nurse (voice)
Ignacio Serricchio
(voice) / Prowler (voice) / Focus Group Tester (voice)
Chris Regan
Preston Lloyd (voice)
Peter Macon
Francis Griffin (voice)
Charles Durning
Mrs. Kraner / Sandy Belford (voice) / Janet
Debra Wilson
Richard Gere (voice) / Hand #1 (voice) / Rupert (voice)
David Boat
(voice) / Jason Voorhees (voice) / Vacuum Repairman (voice)
Jackson Douglas
(voice) / Courtney / Sandra (voice)
Heléne Yorke
Garth Brooks (voice) / George H. W. Bush / Johnny Depp (voice)
Ross Marquand
Chinese Woman (voice) / Yoko Oyes (voice) / Waitress (voice)
Charlet Chung
Stella (voice)
Marlee Matlin
Henessy (voice) / Big Fat Paulie (voice) / Bronx Guy #1 (voice)
Michael Chiklis
Ms. Hobson / Kim Cattrall (voice) / Daycare Teacher
Mo Collins
Isaac (voice) / Australian Man (voice) / Wombat (voice)
Liam McIntyre
Vinny (voice) / Tony Sirico
Tony Sirico
Abusive Father (voice) / Customer (voice) / Gym Instructor (voice)
Khary Payton
Cellmate (voice) / Drug Dealer (voice) / Tony Montana (voice)
Rolando Molina
(voice) / Dean Martin (voice) / Millipede (voice)
Chris Diamantopoulos