Capt. Ed Mercer
Seth MacFarlane
Cmdr. Kelly Grayson
Adrianne Palicki
Dr. Claire Finn
Penny Johnson Jerald
Lt. Gordon Malloy
Scott Grimes
Lt. Cmdr. Bortus
Peter Macon
Lt. Talla Keyali
Jessica Szohr
John LaMarr
J. Lee
Isaac
Mark Jackson
Klyden
Chad L. Coleman
Ensign Charly Burke
Anne Winters
Admiral Halsey
Victor Garber
Yaphit (voice)
Norm Macdonald
Dinal
Elizabeth Gillies
Flight Attendant
Gina Comparetto
Alara Kitan
Halston Sage
Lieutenant
Farelle Walker
Marcus Finn
BJ Tanner
Ty Finn
Kai Wener
Teacher
Eric Satterberg
Girl
Morgan Bastin
Boy
Ray Benson
Lieutenant Turco / Ensign Turco
Kyra Santoro
Male Student #1
Sam Lant
Admiral Ozawa
Kelly Hu
Steve Newton
Larry Joe Campbell
Male Student #2
Braxton Beckham
Computer (voice) / Computer Voice (V.O.) (voice) / Computer Voice (voice)
Rachael MacFarlane
Popular Girl
Jessica Belkin
Student
Dmitri Schuyler-Linch
Topa
Blesson Yates
Bully #1
Shawn Patrick Clifford
Admiral Perry / Perry
Ted Danson
Cassius
Chris Johnson
Bully #3
Chad Guerrero Jr.
Kaylon Primary / Kaylon / K-1
Graham Hamilton
Krill
Sean Patrick Bryan
Brosk
Jim Mahoney
Rachel Shimko