Charlie Harper

Charlie Sheen

Alan Harper

Jon Cryer

Jake Harper

Angus T. Jones

Berta

Conchata Ferrell

Rose

Melanie Lynskey

Judith Harper

Marin Hinkle

Evelyn Harper

Holland Taylor

Kandi

April Bowlby

Nick / Petey / Doug

Joel Murray

Danielle Stewert

Brooke Shields

Rodney

Frankie Jay Allison

Donna

Morgan Fairchild

Lydia

Katherine LaNasa

Naomi

Sara Rue

Dr. Linda Freeman

Jane Lynch

Roger

Wayne Wilderson

Kate / Robin

Brooke D'Orsay

Vicki

Danielle Bisutti

Vanessa

Deprise D Brescia

Lena

Andrea Savage

Detective

Ben Hermes

Taylor

Melanie Abramoff

Teddy Leopold

Robert Wagner

Steven Tyler

Steven Tyler

Herb / Dr. Melnick

Ryan Stiles

Beverly

Allison Janney

Fernando

Enrique Iglesias

Hugo

Mike Connors

Hector

Marco Sanchez

Bridget Schmidt / Myra / Danny

Judy Greer

Joel

Christopher Neiman

Ronald Wiedermeier

Andy Mackenzie

Eva

Carly Thomas

Sam

Brian Patrick Wade

Arnold

Christopher T. Wood

Megan

Molly Morgan

Nina

Rachel Cannon

Jim

Doug Mitchell

Janie

Natalie Denise Sperl

Philip

Tony Tripoli

Kelly

Kelly King

Greg

Matt Roth

Leanne

Rebecca McFarland

Woman

Ireesha

Walden Schmidt

Ashton Kutcher

Police Helicopter Pilot

John Pirruccello

Gordon / Ted

J.D. Walsh

Officer Chamberlain

Andre Ware

Guest Star

Deirdre Lovejoy

Stephan "Bobby" Wasserstein

James Edson

Jeanie

Nadine Ellis

Bruno

Lamont Thompson

Sophie

Kay Panabaker

Pam

Carrie Stevens

Dottie

Nectar Rose

Jamal

Ian "Blaze" Kelly

Bethany

Sara Erikson

Darlene Weidermeier

Julianne Grossman

Sheri

Andrea Lynn Silvers

Changpu

Austin Lee

Hiroshi

Sab Shimono

Sally

Marisa Tayui

Woman's Voice

Nancy Linari

Officer Smith

Michael Patrick McGill

Dr. Prajneep

Kris Iyer

TV Announcer (voice) / Announcer / Pilot (voice)

Robert Clotworthy

Tailor

Avner Garbi

Peggy

Lee Garlington

Referee

Bob Rusch

Sally

Marisa Tayui

Shannon

Lauren Rose Lewis

Andy

Andy Pessoa

Nurse Shelby

Treisa Gary

Cashier

Kevin Knight

Woman

Dale Waddington

Policeman 1

Larry Cedar

Girl at Meeting

Nicole Kreuzer

Lyndsey Mackelroy

Courtney Thorne-Smith

Gangster 2

Jim Meskimen

Minister

Bob Rumnock

Photographer

Michael Merton

Officer Roberts

Bruno Amato

Tina

Sandra McCoy

Tiffany

Jacqueline Lord

Snack Bar Cashier

Shon Little

Pregnant Woman

Rebecca Avery

Joey

Brandon Killham

Dorothy

Susan Sullivan

Det. Grimes

Karen Baughm

Cindy

Mia Kelly

Gloria

Jessica Collins

Chelsea / Suzanne / Tina

Jennifer Taylor

Officer Foster

Stefan Umstead

Middle-Aged Guy

Brendan Patrick Connor

Cindy

Mia Kelly

Amber

Charity Hodges

Shannon

Tammy Lauren

Hot Topic Employee

Juan Jose Dubon

Marie

Katie Weaver

Man

Shane Woodson

Teenage Boy

Daniel Benson

Man

John Dewis

Teenage Girl 1

Annie Mumolo

Jenny

Amber Tamblyn

Man

John Dewis

Woman

Leah Fitzpatrick

Teenage Girl 2

Ashley Edner

Zoey

Sophie Winkleman

Woman

Leah Fitzpatrick

Movie Theater Date

Izabel Goulart

Eldridge Mackelroy

Graham Patrick Martin

Mia

Emmanuelle Vaugier

Salina

Kelley Daugherty

Guest Star

April Betts

Salina

Kelley Daugherty

Melissa

Kelly Stables

Larry

D. B. Sweeney

Ms. McMartin

Maggie Lawson

Courtney

Jenny McCarthy-Wahlberg

Barry

Clark Duke

Robin Schmidt

Mimi Rogers

Gretchen

Kimberly Williams-Paisley

Russell

Martin Mull

Linda

Ming-Na Wen

Party goer

April Betts

Billy Stanhope

Patton Oswalt

Brooke

Aly Michalka

Ava

Talyan Wright

Malibu Surfer

George Katt

Director

Jeff Melman

Director

Gary Halvorson

Director

Ted Wass

Director

Lee Aronsohn

Director

Jon Cryer

Director

James Widdoes

Director

Jerry Zaks

Director

Chuck Lorre

Director

Pamela Fryman